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"Lack of Cleaning" in Brain Cells is Central to Alzheimer’s Disease
An international research team has created a better understanding of Alzheimer's. They have shown that the cleaning system of the brain cells, the so-called mitophagy, is very weakened in animals and humans with Alzheimer's. And when they improve the cleaning system in the animals, the Alzheimer's symptoms almost disappear.
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Lung Therapy Targets Derived From Fetal Signaling Pathways
Specialized lung cells appear in the developing fetus much earlier than scientists previously thought.
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Great White Shark Genome Decoded
In a major scientific step to understand the biology of this iconic apex predator and sharks in general, the entire genome of the white shark has now been decoded in detail.
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Can We Trust Scientific Discoveries Made Using Machine Learning?
Rice University statistician Genevera Allen says scientists must keep questioning the accuracy and reproducibility of scientific discoveries made by machine-learning techniques until researchers develop new computational systems that can critique themselves.
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Needle-shaped Sensors Can Detect Multiple Sepsis Indicators
The device takes a pin prick of blood which is then put on the chip for the result to be read. Its needle shape means it could also be implanted and used on patients in intensive care.
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Speedy Detection of Cryptosporidium Contamination
Using a small and inexpensive biosensor, researchers have developed a novel low-cost technique that quickly and accurately detects cryptosporidium contamination in water samples.
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One Year Later: CRISPR Success in Duchenne Muscular Dystrophy Model
Researchers have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.
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3D Protein Structure Aids Anti-cancer Drug Design
A research team has discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors. Their findings reveal a novel binding site that will promote drug design of more efficient E1 inhibitors.
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Can Fear Memories Be Extinguished?
Researchers have discovered a DNA modification that enhances our ability to extinguish fear. The findings could help guide the development of new treatments for fear-related anxiety disorders.
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The "Backdoor" Path to Masculinity
Scientists have identified for the first time the details of an ‘alternative’ biological process required to develop male genitals in an unborn baby.
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