News

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

Bacterial biofilms are typically the target of heavy-duty cleaning regimens, but these films aren’t always bad news. In fact, growing them on thin sheets of nanofibers is a great way to produce a fermented milk product that can deliver hardy probiotics to the digestive tract.

A new study reveals regeneration of amputated body parts is not always an ancient trait and scientists might need to rethink the way they compare animals with regenerative abilities.

Melanoma, the deadliest form of skin cancer, is diagnosed in more than 130,000 people globally every year. Now, work is being done on a tool to help in its early detection: a simple, compact laser probe that can distinguish between harmless moles and cancerous ones – in a matter of seconds.

Researchers have found a compound that may treat inflammatory bowel disease (IBD) without directly targeting inflammation. The compound tamps down the activity of a gene linked to blood clotting.

Researchers report in Nature why the liver is the most common site of metastatic disease. Their research shows that hepatocytes coordinate myeloid cell accumulation and liver fibrosis (the thickening and scarring of tissue) which increases the organ’s susceptibility to cancer cells.

Scientists have identified a genetic mechanism that may play a role in at least 10 percent of all obesity cases.

Through the use of resting-state functional magnetic resonance imaging, reproducible brain connectivity patterns were identified in people with autism. However, as these phenotypes were only moderately linked to clinical symptoms, the usability of this imaging alone is limited as a diagnostic tool.

The Pistoia Alliance, a global not-for-profit that works to lower barriers to innovation in life sciences R&D, today released proof of concept (PoC) software to enable the digitisation of analytical method descriptions, as part of its Method Database (MethodDB) project.

Researchers have discovered a mechanism that gives human cells a chance to stop piling up mutations when cells replicate and divide in the body.