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Flipping the View: Microscope Could Help Gauge Drug Properties

A new type of microscope, based on concepts of phase-contrast microscopy, may give doctors a better idea of how safely and effectively a medication will perform in the body.
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Incredible Microbial Diversity in "Inhospitable" Locations

A sapphire blue hot spring 8,600 feet above sea level on the Continental Divide, where volcanic gases rise to mix with snowmelt and rainwater, is home to exceptionally diverse microbes.
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Vietnam Still Suffering With Pollutants From Agent Orange

Scientists have documented the environmental legacy of Agent Orange in Vietnam, including hotspots where harmful dioxin continues to enter the food supply.
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Grim Picture of Fast Food Evolution

Despite the addition of some healthful menu items, fast food is even more unhealthy for you than it was 30 years ago, with significant increases in calories, sodium and portion sizes.
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Unraveling DNA Replication Mysteries

DNA replication is a complex process in which a helicase ring separates the DNA molecule's two entwined and encoded strands, allowing each to precisely reproduce its missing half. Researchers have discovered how the helicase--a donut-shaped enzyme composed of six identical proteins--is able to thread just one of the strands when they are bound together. Now, researchers have solved the mystery.
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Researchers "Bait" Proteins Behind Neurodegeneration

A single misbehaving protein – called TDP-43 – is behind 97 percent of amyotrophic lateral sclerosis (ALS) cases and 45 percent of frontotemporal dementia diagnoses. It also is found in 80 percent of chronic traumatic encephalopathy and 60 percent of Alzheimer’s disease cases. Now, researchers have found a way to trap TDP-43 so it doesn’t form toxic clumps that can cause neurodegeneration.
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HIIT Back: Colon Cancer Growth Reduced by Exercise

Exercise may play a role in reducing the growth of colon cancer cells according to new research published in The Journal of Physiology. The study found that after a short session of high intensity interval training (HIIT), growth of colon cancer cells was reduced, and this also increased indicators of inflammation.
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Now You See It, Now You Don't

An inexpensive, easy-to-produce film that makes objects completely invisible to infrared detectors is now a reality.
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What Controls the Tips of Our Chromosomes?

Telomeres work as a protective cap that prevents our genetic material from unfolding and corroding away. In a study now published in EMBO Journal, a research team , discovered a key aspect of the regulation of telomeres.
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Reprogramming Rapamycin to Create New Small Molecule Drugs

A team of researchers at Johns Hopkins University and the Institute of Biotechnology at the University of Helsinki have succeeded in developing a completely new strategy that allows the creation and discovery of new small-molecule drugs with unprecedented drug-like properties.

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