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Be Yourself at Work — It’s Healthier and More Productive
At work, it’s healthier and more productive just to be yourself, according to a new study. It examines 65 studies focusing on what happens after people in a workplace disclose a stigmatized identity, such as sexual orientation, mental illness, physical disability or pregnancy.
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Defective Cellular Waste Disposal Provides Insight into ALS
A study improves our understanding of how amyotrophic lateral sclerosis develops. A common feature of this condition is an imbalance between the synthesis and degradation of proteins within cells. The researchers discovered that mutated ubiquilin proteins that cause ALS fail to regulate the function of lysosomes, a key ‘waste disposal and recycling center’ of the cells.
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Manipulating Cell Networks With Light – New Frontiers in Optical Microscopy
A new optical microscope system called SIFOM (Stimulation and Imaging-based Functional Optical Microscopy) can stimulate multiple cells simultaneously by a holographic method and monitor cell activity after the stimulation using 3D measurements based on fluorescence holography.
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Walk Like a Bacteria
Biophysicists have been able to directly study the way bacteria move on surfaces, revealing a molecular machinery reminiscent of motor reflexes.
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Brain Scans Shine Light on How We Solve Clues
What’s an s-shaped animal with scales and no legs? What has big ears, a trunk and tusks? What goes ‘woof’ and chases cats? The brain’s ability to reconstruct facts – ‘a snake’, ‘an elephant’ and ‘a dog’ – from clues has been observed using brain scanning by researchers at Aalto university.
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Gene May Predict the Development of Pancreatic Cancer
Mayo Clinic researchers have identified a gene called "UCP-1" that may predict the development of pancreatic cancer in people with Type 2 diabetes.
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Could Targeting T Cell Metabolism Improve Immunotherapy?
Rescuing T cell glycolysis could help T cells maintain the ability to compete with cancer cells, and improve responsiveness to cancer immunotherapy.
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Potential Therapeutic Target for Colon Cancer
Researchers have pinpointed a set of enzymes involved in tumor growth that could be targeted to prevent or treat colon cancer.
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Fetal Growth Inhibited by Mothers Exposure to Perfluorinated Substances
For the first time, researchers have shown that a combination of perfluorinated substances, which can mimic estrogen, in the mother significantly inhibits children's growth.
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CRISPR Tool Targets Neurons
A powerful new tool is available for neuroscience investigation into brain development, the mechanisms of memory and learning, and the role of brain dysregulation in neuropsychiatric diseases like addiction, depression, schizophrenia and Alzheimer’s disease.
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