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"Turn-on" Fluorescence Shines Light on Protein Misfolding
A team of researchers from Penn State and the University of Washington re-engineered a fluorescent compound and developed a method to simultaneously light up two different proteins as they misfold and aggregate inside a living cell
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Movement Impairments Reversible in Autism Mouse Model
Researchers from Cardiff University have established a link between a genetic mutation and developmental movement impairments in autism.
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Why a Neuronal "Call for Help" Leads to an Inflammatory Cascade in Parkinson's Disease
Working in two fruit fly models of Parkinson’s disease, researchers at the Buck Institute have characterized a novel molecular mechanism that orchestrates a harmful cascade of inflammatory signaling and demonstrated that its disruption protects neurons as they age.
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How Music Activates Our Brain's Reward Center
New research shows the musically unexpected activates the reward center of our brains, and makes us learn about the music as we listen - the first evidence that musically elicited reward prediction errors cause musical pleasure. It is also the first time an aesthetic reward such as music has been shown to create such a response.
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Using Marine Snail Insulin to Improve Diabetes Treatments
Researchers at University of Utah Health detailed the function of cone snail insulins, bringing them one step closer to developing a faster-acting insulin to treat diabetes.
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Why Does Bribery Work?
A new study from Carnegie Mellon University suggests that greed, and not the willingness to return the favor, is the main reason people give in to bribery. But the research also finds there are times when the almighty buck can be ignored and effects of a bribe can be lessened.
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Why Too Much DNA Repair Can Injure Tissue
In certain situations, DNA repair can become harmful to cells, provoking an inflammatory response that produces severe tissue damage.
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Antidepressant Based on Ketamine Gets Backing From FDA Advisory Group
A form of the hallucinogenic party drug ketamine has cleared one of the final hurdles toward clinical use as an antidepressant. During a meeting at the US Food and Drug Administration (FDA) in Silver Spring, Maryland, an independent advisory panel voted 14-2 in favor of recommending a compound known as esketamine for use in treating depression.
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Sleeping Off Infection
Researchers have discovered why sleep can sometimes be the best medicine, potentially improving the ability of some of the body’s immune cells to attach to their targets.
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Meet the "Scientist That Never Sleeps"
Researchers have developed a new AI-driven platform that can analyse how pathogens infect our cells with the precision of a trained biologist. The platform, HRMAn (‘Herman’), which stands for Host Response to Microbe Analysis, is open-source, easy-to-use and can be tailored for different pathogens including Salmonella enterica.
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