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Oral Chemotherapy to be Trialed
An experimental chemotherapy drug that can be taken orally is moving into early phase clinical trials.
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CRISPR and Infertility: Mutation Disrupts Embryo Implantation
Researchers have designed a CRISPR-Cas9 gene editing screen to study the genes involved in the pre- and post-implantation stages of embryonic development.
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Indoor Smoking Bans Insufficient to Protect
Not smoking around children doesn’t stop the children of smokers from being exposed to nicotine, with potentially hazardous chemicals that stain the walls, ceilings, carpet, upholstery and their hands.
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The Gut's Influence in Parkinson's Disease: Hype or Hope?
There is growing evidence that at least in some patients with Parkinson's disease (PD), the disease may begin in the gut. Writing in an open access special supplement to the Journal of Parkinson's Disease, experts explore the last two decades of research about the gut–brain axis in PD and look ahead at the possible development and impact of these research areas in the next two decades.
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Normal Brain Aging Patterns Occur at a Faster Rate in People With Psychosis
Accelerated aging of cognitive networks after illness onset offers potential for early intervention, according to a study in Biological Psychiatry.
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Tiny Fish Can Recognize Itself in the Mirror
The ability to perceive and recognize a reflected mirror image as self is considered a hallmark of cognition across species. Now researchers report that cleaner wrasse respond to their reflection and attempt to remove marks on its body during the mirror test.
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Seafood Mislabeling a Persistent Problem
Not only does Canada continue to have a problem with fish mislabeling, but that problem persists throughout the supply chain.
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Mega Docking Library Set to Speed Drug Discovery
Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such “make-on-demand” compounds readily available to scientists for chemical biology and drug discovery.
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RNA Encourages Protein Aggregation in Neurodegenerative Disease
New research reveals RNAs, which are crucial for cells to produce proteins, are also involved in protein aggregation, where proteins do not fold properly and 'clump' together into aggregates.
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Exosome-hacking Boosts Leishmania Infections
The LVR1 virus infects ancient eukaryotes called Leishmania, causing debilitating lesions and ulcers. This study has revealed that viral RNA is exposed to host cells via exosomes, tiny cell-derived vesicles that reside in most bodily fluids.
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