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Researchers Identify Genes Involved in Immune System Regulation
Using the novel genome editing technique, CRISPR, a team of researchers at the Wellcome Sanger Institute have isolated the genes involved in regulating T helper cell activation. The study, conducted in mice using T helper type 2 (Th2) cell lines, was recently published in the journal Cell.
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How Drugs Can Minimize Side Effects of Chemo
Researchers at the University of Zurich have determined the three-dimensional structure of the receptor that causes nausea and vomiting as a result of cancer chemotherapy. The study explains for the first time why some drugs work particularly well in ameliorating these side effects.
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Antimicrobial Peptides Freeze Cytoplasmic Motion, Render Bacteria Susceptible to Attack
A previously unknown mechanism has been revealed for LL-37 and similar peptides, which are being tested in early-stage clinical trials for treating infections resistant to classical antibiotics.
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Predicting Anti-Diabetes Drug Response Using Fat Cell Genetics
In a new study published in Cell Stem Cell, a team of researchers have demonstrated, using fat cells derived from human stem cells, that individual genetic variation can be used to predict whether the TZD rosiglitazone will produce the unwanted side effect of increasing cholesterol levels in certain individuals.
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HIV Undetectable Equals Untransmittable
An overwhelming body of clinical evidence has firmly established the HIV Undetectable = Untransmittable (U=U) concept as scientifically sound, providing important guidance for HIV prevention.
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Phat on Potential, Lipidomics Is Gaining Weight
Researchers are pounding out research to further understand the complex nature of lipids.
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Major Progress for Rare Autoimmune Syndrome Gene Therapy
This gene therapy is similar to the technique the lab has used against another immune disease—severe combined immune deficiency, also known as bubble baby disease.
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Flossing Linked to Increased PFAS Levels in the Body
A new study suggests certain types of consumer behaviors, including flossing, contribute to elevated levels in the body of toxic PFAS chemicals.
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Drug Suppresses Formation of Metastases
The most deadly aspect of breast cancer is metastasis. It spreads cancer cells throughout the body. Researchers have now discovered a substance that suppresses the formation of metastases.
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Mo' Pain, Less Gain for a Brain on Cocaine
A new study shows how the release of the neurotransmitter dopamine changes when working for cocaine. Our brains naturally release dopamine to reward us for working hard for something gratifying, for example, a sweet piece of chocolate. Yet when it comes to illicit substances such as cocaine, the harder the effort put into getting cocaine, the less likely there will be a large jolt of dopamine.
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