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Blood-brain Barrier Breakdown Early Marker of Human Cognitive Dysfunction

Individuals with early cognitive function develop brain capillary damage and blood-brain barrier breakdown in the hippocampus, regardless of amyloid beta/tau biomarker changes.
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Which One is George?

George is a zebrafish. Along with Tom and 98 other mates, George swims freely in a laboratory tank at the Champalimaud Centre for the Unknown (CCU), in Lisbon, Portugal. Question: is it possible to identify, from video images, which fish is which at every moment? Yes, say researchers who have built a software, called idtracker.ai (where “ai” stands for artificial intelligence, or AI) that can do the job quickly and with extreme accuracy.
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Precise Measuring Tool for Optimal Antibody Effectiveness

Using DNA origami scientists have been able to demonstrate the most accurate distance between densely packed antigens in order to get the strongest bond to antibodies in the immune system.
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Using Sound Waves to Prevent Small Chemical Reactors from Clogging Up

Companies are keen to use miniature chemical reactors to make pharmaceuticals and fine chemicals, but are discouraged by their tendency to clog up. Researchers at KU Leuven have now devised an elegant way of using sound waves to keep the chemicals flowing.
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The Human Brain Works Backwards to Retrieve Memories

When we remember a past event, the human brain reconstructs that experience in reverse order, according to a new study at the University of Birmingham.

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Researchers Pioneer Machine Learning to Speed Chemical Discoveries, Reduce Waste

Researchers are tapping a new set of capabilities in this field of artificial intelligence, combining artificial neural networks with infrared thermal imaging to control and interpret chemical reactions with precision and speed that far outpace conventional methods.
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Marine Bacterium Reveals How Cells Control Toxic Metals

An ocean-dwelling bacterium has provided fresh insights into how cells protect themselves from the toxic effects of metal ions such as iron and copper.
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Long-sought Activator of Sigma-1 Receptors in Human Cells

A new study shows that choline, an essential nutrient that functions in metabolism, is an endogenous activator of sigma-1 receptors, marking an important advance in cell biology.
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Poor Diet Could Lead to Heart Disease in Future Generations

Scientists have identified an epigenetic marker and two genes that caused heart failure in the children and grandchildren of fruit flies with high-fat-diet-induced heart dysfunction.
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The Trouble With Tasting

Geographic location is a factor affecting how Canadian wine experts rate quality, as well as some of wine’s sensory attributes — things like balance and acidity.
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