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Induced Neuronal Cells Validated on an Epigenomic Level
Methyl groups of neurons derived from mouse fibroblast cells match those from naturally developed cells, providing further validation of these cells as a suitable model for research.
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$11M Study to Jumpstart Radiation Exposure Drug Development
The U.S. Department of Defense has turned to the University of Nebraska to jumpstart the development of drug therapies to protect military service members from the effects of radiation exposure.
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Poor Road Surfaces Boost Pollution
Keeping road surfaces in good shape saves money and energy and reduces greenhouse gas emissions, more than offsetting pollution generated during road construction.
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Fasting to Protect Against Aging-Associated Diseases
Researchers have found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases.
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Watching TV Under fMRI
With a little help from HBO’s “Curb Your Enthusiasm,” neurobiologists have uncovered a key component of how the human brain marks time. Using high-powered functional MRI on college students watching the popular TV show, they were able to capture the processes by which the brain stores information related to when events happen, or what is known as temporal memory.
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Hindering Melanoma Metastasis with FDA-approved Drug
An FDA-approved drug has been identified that, when used with surgery, hampers metastasis in an animal model. Originally developed and approved ~65 years ago to control blood pressure, the medication resperine also prevents what are known as tumor-derived extracellular vesicles from fusing to healthy cells and sharing their cargo of disease-promoting molecules.
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Altering Stathmin2 Expression Rescues Motor Neuron Growth
Research led by stem cell scientists at Harvard University points to a potential new biomarker and drug target for amyotrophic lateral sclerosis (ALS), a neurological disease that is difficult to diagnose and treat.
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Window into Salmonella Strain Ravaging Sub-Saharan Africa
Scientists have completed one of the largest bacterial comparative gene expression studies to date, to aid understanding of the bacteria causing a devastating Salmonella epidemic in sub-Saharan Africa.
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Mouse Study Suggests Stroke Drug May Prevent Alzheimer’s Disease
Researchers have discovered that a drug currently being developed to treat stroke patients could also prevent Alzheimer's disease.
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Halting Inflammation at the Flick of a Switch
A novel regulator of the immune system has been identified that deactivates the innate immune system and could prevent certain diseases caused by an excessive activation of the immune system.
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