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Is the "Humanized" Mouse an Appropriate Model for Vaccine Studies?
A new systematic way of comparing immune responses of "humanized" mice versus humans has been used to show that a newly developed "humanized" mouse shares significant immune-system responses with humans.
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On-demand Biologics
Many life-saving medicines, including insulin, antibodies and vaccines, are derived from living cells. These “biologics” can be difficult to obtain and store on the battlefield or in remote areas. That’s why scientists are trying to develop portable systems that can quickly manufacture small batches of protein therapeutics on demand.
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Blue Brain Project Releases Pioneering 3D Brain Cell Atlas
Like “going from hand-drawn maps to Google Earth,” the Blue Brain Cell Atlas allows anyone to visualize every region in the mouse brain, cell-by-cell – and freely download data for new analyses and modelling.
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Tapping into Water Quality Worries
Routine testing for most prospective contaminants is carried out before water is distributed to homes, not where it’s used. Consequently some consumers are exposed to contaminant mixtures that aren’t commonly monitored.
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Blue Brain Project Releases Pioneering 3D Brain Cell Atlas
Like “going from hand-drawn maps to Google Earth,” the Blue Brain Cell Atlas allows anyone to visualize every region in the mouse brain, cell-by-cell – and freely download data for new analyses and modelling.
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Technique for Identifying ‘Small’ Molecules Could Accelerate Drug Discovery & Manufacturing
A UCLA-led team of scientists has developed a new technique that will enable researchers to easily and quickly determine the structures of organic molecules using very small samples.
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Know Your Nuts
Consumers and processors are willing to pay more for better nuts. Therefore testing methods are needed to reliably authenticate the nuts’ country of origin and NMR analysis could fit the bill.
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Two Clinically-approved Antibiotics Eliminate Senescent Cells Associated with Ageing
While a closely-related compound did not show any senolytic activity, Azithromycin and Roxithromycin (two clinically-approved antibiotics) induced aerobic glycolysis and autophagy in human fibroblast cell lines. The findings have significant implications for alleviating ageing-associated diseases.
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Resilience May Be Linked to Brain Connectivity
Neighborhood violence has been associated with adverse health effects on youth, including sleep loss, asthma and metabolic syndrome. Yet some youth living in high-crime neighborhoods manage to avoid these effects. A new study aims to answer a resilience puzzle: Why does a second-hand or indirect experience of neighborhood violence affect some youth, but not others?
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Why Cancers Form in Specific Cell Types
Researchers have adapted a revolutionary new technology called single-cell RNA sequencing to study gene expression in individual cells.
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