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Cryo-EM Reveals Potential Drug Target for Neurological Conditions
A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the atomic-level structure of TRPM2, a protein that may be a promising drug target for conditions such as Alzheimer's disease and bipolar disorder.
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'Gene Drive' Technology Wipes Out Lab Mosquitoes
Researchers have eliminated caged mosquitoes using ‘gene drive’ technology to spread a genetic modification that blocks female reproduction.
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Gene Therapy Eliminates Mutant Mitochondria DNA in Mouse Heart
Using gene therapy, researchers have eliminated damaged DNA in mitochondrial diseases, in a mouse model.
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What can we Tell from Your Smell?
Bodily odors of otherwise healthy animals sharing an environment with sick animals become like the odors of the sick animals.
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Breakthrough in Controlling the 3D Structure of Molecules
New drug discovery has long been limited by researchers’ inability to precisely control the 3D structure of molecules. But a team has made a major breakthrough in chemical synthesis that now makes it possible to quickly and reliably modify the 3D structure of molecules used in drug discovery,
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Diagnosis of Multi-resistant Hospital Pathogens Fast-tracked
This procedure accelerates the diagnosis of multi-resistant hospital pathogens, showing promise for clinical applications.
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Ancient Predator Teeth Could Regenerate
A team of palaeontologists have been able to discover more about how earliest predators were able to grow and regenerate their teeth.
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Protein “Trafficker” Implicated in Autism and Other Brain Disorders
Findings suggest that protein ASTN2 is a key regulator of dynamic trafficking of synaptic proteins and lend support to the idea that aberrant regulation of protein homeostasis in neurons is a contributing cause of complex neurodevelopmental disorders.
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Robotic Skin Gets the Spray Treatment
Researchers have developed a spray on tactile sensor that could help robotic surfaces mimic the sensing capabilities of human skin.
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Trojan Horse Delivery for Treating Rare Blood-clotting Disorder
Platelet blood cells can carry an enzyme needed to prevent clots, while hiding it from autoantibody neutralization.
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