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Small Molecule Drug, ONC201, Kills Breast Cancer Cells by Targeting Mitochondria
Researchers identify a novel mechanism of action of ONC201 as a mitochondria-targeting drug in cancer cells. ONC201 was originally identified as a small molecule that induces transcription of TNF-related apoptosis-inducing ligand (TRAIL) and subsequently kills cancer cells by activating TRAIL death receptors.
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Patents Secured for Promising Cannabinoid Pain-patch
“We shared our pain-patch with leading pain doctors in the region and they were all excited”; Preliminary studies on pain-patch shows excellent results” said Bobban Subhadra, M.S., Ph.D, Chief Operating Officer of Apotheca.
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Biochemically Altered Myelin Triggers MS, Not Autoimmune Attack
Study challenges conventional thinking about the cause of multiple sclerosis.
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Certified Seal Launched to Guarantee Cannabis Product Quality in California
With the launch of the BASInfused™ certified seal, cannabis consumers will be safe in the knowledge that the products they consume are safe and labeled correctly.
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A Cure for Baldness on the Horizon?
A new drug could ease the distress of men and women who suffer from baldness, according to researchers from The University of Manchester’s Centre for Dermatology Research.
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Peptide Therapy Ends Insatiable Hunger in Genetically Obese Patients
In most cases of obesity, genetics and environment influences both have input. For obese patients with mutations in the leptin receptor LEPR, genetics are the chief drivers of their extreme body weight. LEPR mutations cause insatiable hunger, but a new study has shown efficacy in controlling these insatiable appetites.
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Unravelling Pore-Forming Bacterial Toxins
Pore-forming toxins are common bacterial poisons, attack organisms by introducing holes in cell membranes. Combining crystallographic and cryo-electron microscopy methods, scientists have now unravelled the mechanism of action for one of these toxins. The findings could help combat associated diseases and advance crop protection.
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Metastasis Enablers: Key to Creating Ovarian Cancer Treatments
New research has identified one way ovarian cancer cells appear to successfully spread. The work, detailed in the journal Cancer Research, could lead to new therapies to curb metastasis of these tumors.
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Noise-Induced Hearing Loss Prevented: Simple solution saves sound sensing cells
Study sheds light on how noise-induced hearing loss happens and shows how a simple injection of a salt- or sugar-based solution into the middle ear may preserve hearing.
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Experts Discuss Role of Cannabis in the Opioid Crisis
The panel discussion covered the barriers to understanding how cannabis can be used to alleviate chronic pain and potentially ease the opioid crisis.
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