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New Method Speeds Up Drug Development
One of the key steps in developing new drugs is determining the atomic structure of its biologically active substances. A research group has now modified a method that had previously been used exclusively for the crystallization of proteins, and successfully applied it to organic salts.
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Drug Could Stop Cancer-Causing Gene in its Tracks
Michigan State University scientists are testing a promising drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing.
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New Measures Announced to Stop Babies Being Exposed to Valproate in the Womb
New regulatory measures around sodium valproate, 'a landmark moment for all women who have ever been prescribed the epilepsy drug.'
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Boosting Rice Growth in Salty Soil
Activating a gene that improves rice's tolerance to salt stress will make the crop far hardier in salty soil, new research suggests.
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Frozen Corn Likely Source of Ongoing Listeria monocytogenes Outbreak
Frozen corn is the likely source of an outbreak of Listeria monocytogenes which has affected five EU Member States (Austria, Denmark, Finland, Sweden, and the United Kingdom) since 2015. As of 8 March 2018, 32 cases including six deaths had been reported.
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Western Diet Depletes Artery-Protecting Immune Cells
Scientists show how immune cells that shield arteries from inflammation are reprogrammed into cells that promote inflammation by high levels of fats and cholesterol.
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Bystander T Cells Can Steal the Show in Resolving Inflammation
Researchers show that non-specific bystander T cells can play an active role in countering type 1 diabetes.
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Filling the "Black Holes of the Genome"
15 years on from the "completion" of the Human Genome Project, gaps still remain in our index of human genetic material. The production of the first complete linear map of our Y chromosome's centromere shows these blanks are being slowly but steadily filled in.
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Captured on Film for the First Time: Microglia nibbling on brain synapses
Researchers have captured microglia nibbling on brain synapses. Their findings show that the special glial cells help synapses grow and rearrange, demonstrating the essential role of microglia in brain development.
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Swiss Army Knife of Protein Interactions
Researchers introduce an optimized and integrated approach combining affinity purification mass spectrometry and BioID in a single workflow for interaction proteomics. As they describe it, it proves almost as versatile as the Swiss Army Knife.
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