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Uncovering How Alcohol-derived Metabolites Damage the Genome of Stem Cells

Using genetically engineered mice that lack key genes for aldehyde removal and DNA repair, researchers have found that aldehydes damage DNA in the crucial stem cells that produce blood.
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Big Step Towards Building a Better Opioid

Scientists have solved the crystal structure of the activated kappa opioid receptor bound to a morphine derivative. They then created a new drug-like compound that activates only that receptor, a key step in the development of new pain medications.
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The Window for Saving the World’s Coral Reefs is Rapidly Closing

For the first time, researchers have measured the escalating rate of coral bleaching at locations throughout the tropics over the past four decades. The study documents a dramatic shortening of the gap between pairs of bleaching events, threatening the future existence of these iconic ecosystems and the livelihoods of many millions of people.
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New Research Hub to Tackle Global Vaccination Challenges

The University of Bristol will contribute to a new research hub to increase global immunisation coverage and improve response to viral outbreaks through the rapid and cost-effective deployment of vaccines.
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Stem Cell Therapy for Eye Disease Brought Closer to the Clinic

Scientists at the National Eye Institute (NEI), part of the National Institutes of Health, report that tiny tube-like protrusions called primary cilia on cells of the retinal pigment epithelium (RPE)—a layer of cells in the back of the eye—are essential for the survival of the retina’s light-sensing photoreceptors.
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Raman Spectroscopy Helps Battery Research

Power generation is shifting from traditional to less predictable renewable sources.
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Sperm-Sorting Device That Could Improve IVF Success Developed

SPARTAN sperm-sorting device uses obstacle course to select fastest and healthiest sperm to help women become pregnant faster.
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Protein Analysis Enables Treatment of Eye-Disease Symptoms with Existing Drugs

By identifying proteins abnormally expressed by patients with a rare eye disease, researchers were able to identify existing drugs that could be used to treat symptoms.
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Illumina and KingMed Diagnostics Partner to Develop Next-Generation Sequencing Technology for Chinese FDA Approval

Companies target review aimed at molecular oncology and hereditary diseases.
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Hairy Skin Grown from Mouse Stem Cells

Researchers at Indiana University School of Medicine have successfully developed a method to grow hairy skin from mouse pluripotent stem cells—a discovery that could lead to new approaches to model disease and new therapies for the treatment of skin disorders and cancers.
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