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Water Cooling for the Earth's Crust
By applying a new analysis method, researchers have now discovered that sea water can penetrate to depths of more than 10 kilometres below the seafloor. This result suggests a stronger cooling effect on the hot mantle.
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A Structural Clue to Attacking Malaria’s ‘Achilles Heel’
Researchers have shed light on how the human immune system recognizes the malaria parasite though investigation of antibodies generated from the RTS,S malaria vaccine. This work could boost the development of a more potent vaccine against the global killer.
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Antibiotic Resistance: Researchers Succeed in Blocking Genes of Resistance
Scientists have come up with a novel approach to block the transfer of resistance genes between bacteria via plasmids. Libraries of small chemical molecules were screened for those that bound an essential component of the plasmid transfer machinery. Analysis by X-ray crystallography revealed the exact binding site of these molecules.
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Meningococcal Vaccine Could Protect Against 91% of Targeted Bacterial Strains
“We are very pleased to see that it looks like the vaccine has the potential to cover most of the strains of meningococcal Group B bacteria currently circulating in the U.S.,” said lead study author Gowrisankar Rajam, Ph.D.
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Protein "Intentionally" Terminates own Synthesis by Destabilizing Synthesis Machinery — the Ribosome
A research group has discovered that a protein, during its synthesis, may destabilize the structure of the ribosome and end its own synthesis prematurely, and found that this phenomenon is used for adapting the cell to its environment.
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Novel Chemistry Technique Simplifies Late-Stage Modification of Drug Compounds
Chemists at The Scripps Research Institute (TSRI) have invented a technique that overcomes a long-standing problem in organic chemistry and should streamline the process of discovery and development for many new drugs.
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Pre-Diabetes Discovery Marks Step Towards Precision Medicine
Identification of three molecules that can be used to accurately assess pre-diabetes – a key predictor of conditions such as diabetes and high blood pressure – has brought precision medicine for humans a step closer.
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Dipstick Technology Enables Rapid Diagnosis Anywhere
A new Australian study has reported a revolutionary dipstick technology that allows DNA and RNA to be extracted from living organisms in as little as 30 seconds.
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Whole-Brain Map of Memory Circuits Constructed from Human Data
The work elucidates the way different regions of the brain communicate during cognitive processes like memory formation.
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Advanced Prostate Cancer: EMA Approves Abiraterone Combined With Hormone Therapy as First-line Treatment
The prostate cancer drug abiraterone has been approved by the European Medicines Agency in combination with standard hormone therapy for use as a first-line treatment for advanced prostate cancer.
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