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Accurately Transcribing DNA Overrides DNA Repair
Researchers have found that in the model organism E. coli, the fidelity of transcribing DNA comes at the expense of DNA repair.
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Researchers Map Human Genome in 4-D as it Folds
The report, which may lead to new ways of understanding genetic diseases, appears on the cover of Cell.
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Antidote to Synthetic Cannabis ‘Spice’ Intoxication Could Be Found in Slimming Drug
Early research from Queen Mary University of London has potentially found an antidote that can rapidly stop the intoxicating effects of cannabis and synthetic cannabinoids.
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A New CRISPR-Engineered Cancer Model to Test Therapeutics
New technique for modeling human leukemia in mice may aid drug discovery and clinical trials.
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CRISPR-Gold Fixes Duchenne Muscular Dystrophy Mutation in Mice
A single injection of CRISPR-Gold into mice with Duchenne muscular dystrophy led to an 18-times-higher correction rate and a two-fold increase in a strength and agility test compared to control groups.
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Rare Benign Tumors Hold the “Genetic Recipe” to Combat Diabetes
Rare benign tumors known as insulinomas contain a complicated wiring diagram for regeneration of insulin-producing human beta cells, which may hold the key to diabetes drug development.
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Study Challenges Oldest Observation in Cancer Metabolism
Scientists have discovered that lactate provides a fuel for growing tumors, challenging a nearly century-old observation known as the Warburg effect.
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Why Can’t mTOR Inhibitors Kill Cancer?
Anti-cancer drugs called mTOR inhibitors slow the growth of cancer cells but show limited ability to cause cancer cell death.
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Stealing from the Body: How Blood Cancer Recharges its Batteries
New research has uncovered how blood cancer ‘steals’ parts of surrounding healthy bone marrow cells to thrive, a finding that that could help form new approaches to cancer treatment in the future.
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New Test Reveals Antibiotic-Resistant Bacteria in 30 Minutes
The new procedure shortens wait times from three days and could help reduce the spread of superbug bacteria.
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