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Commensal Bacteria Make GPCR Ligands, Mimic Human Cell Signalling
Scientists have genetically engineered bacteria to produce molecules that have the potential to treat certain disorders by altering human metabolism.
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Ixolaris to Treat HIV-linked Heart Disease
Study shows an experimental drug from tick saliva may hold promise as a treatment for HIV-linked heart disease.
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Two Distinct Brain Regions Independently Influence Decision Making
Two different, but highly-connected areas necessary for encoding the value and availability of a reward have been identified.
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Automated Whole Cell Patch Clamp Recording In Vivo
Imperial scientists have developed algorithms for successful automated whole cell patch clamp of neurons in vivo.
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Online Game Challenges Players to Design CRISPR On/Off Switch
Online game players are being asked to design an RNA molecule capable of acting as an on/off switch for the gene-editing tool CRISPR/Cas9.
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Placenta-on-a-Chip Mimics Malaria in the Womb
The chip is being designed to provide real-time monitoring of vascular cell well-being and nutrient circulation across the barrier between mother and fetus, and under the influences of the malaria parasite to see how it responds to various drug treatments.
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First Atlas of B-cell Clones in the Human Body Charted
A new “anatomic atlas” of how B cells – the immune system’s producer of antibodies – link up to form networks has been charted.
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An Unusual Delivery Service
Researchers from the University of Bern propose the "alternate import model" of tRNAs, which could help lead to the development of drugs for diseases such as sleeping sickness.
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Alzheimer's Pathology: Inflammation induces neuritic beading and accumulation of abnormal tau
UNC researchers identify two proteins – MMP-9 and HDAC6 – that help promote this harmful, amyloid-to-inflammation-to-tau cascade.
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New Diagnostic Test Could Help Detect Meningitis Faster
The LAMP test can detect meningococcal disease in under an hour, which could lead to faster diagnosis and treatment for patients.
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