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WGS Reveals Potential Pitfalls of In Vivo CRISPR Gene Editing
As CRISPR-Cas9 starts to move into clinical trials, a new study has found that the gene-editing technology can introduce hundreds of unintended mutations into the genome.
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Stem Cells Yield Nature’s Blueprint for Body’s Vasculature
A team from the University of Wisconsin School of Medicine and public Health and the Wisconsin National Primate Research Center have coaxed stem cells to become the cells that make up human veins, arteries and capillaries.
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Gene Variant That Protects Against Heart Disease Identified in Isolated Islanders
A genetic variant that protects the heart against cardiovascular disease has been discovered by researchers at the Wellcome Trust Sanger Institute and their collaborators.
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Epigenetic Markers May be Used to Estimate Anal Cancer Risk
The early research finds that the test could lead to a reduction in painful procedures and minimise the over-treatment of people at low risk.
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Loss of TREM2 in Microglia Significantly Impairs Brain Function
Researchers reveal importance of microglia for brain homeostasis and suggest boosting their protective role in the early stages of dementia could delay the onset of debilitating symptoms.
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Designer Viruses Successfully Stimulate the Immune System to Fight Cancer
These designer viruses alert the immune system and cause it to send killer cells to help fight the tumor.
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Targeting Cell Cycle Protein May Slow Cancer Cell Division
Researchers have identified a new way to potentially slow the fast-growing cells that characterize all types of cancer.
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Sound Source Localization Encoded by Constant Synaptic Delays and Discontinuous Axon Insulation
Researchers reveal the importance of synaptic delays in the auditory brainstem circuitry for encoding sound source localization
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Eisai and Broad Institute Initiative to Further Develop Malaria Treatments
The Eisai and Broad Joint Development Program for Antimalarial Medicines, using hits obtained by initial screening of Broad's compound library for antimalarials as a starting point.
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