News

Results on ARGX-115 published in Science Translational Medicine indicating inhibition of immune checkpoint GARP in in vivo mouse model.

Company to initiate a Phase III trial in Q4 2015.

Data showing OCA treatment increases fibrosis resolution and cirrhosis prevention in high-risk NASH patients.

The study is published in the New England Journal of Medicine.

Despite the abuse potential of opioid drugs, they have long been the best option for patients suffering from severe pain. The drugs interact with receptors on brain cells to tamp down the body’s pain response.

Researchers at University of California, San Diego School of Medicine report a previously unappreciated phenomenon in which the location of injury to a neuron’s communication wire in the spinal cord — the axon — determines whether the neuron simply stabilizes or attempts to regenerate.

Firms partner to improve understanding of in vitro/in vivo correlation for transporter-mediated hepatic clearance, drug-drug interactions, and drug-induced liver injury.

Arthritis Research UK-funded scientists at The University of Manchester have identified a new way in which genotyping can be used to predict disease outcomes among sufferers of rheumatoid arthritis.

A research collaboration spearheaded by ETH Zurich has shed light on the genome of two commercially important species of bumblebees. The findings provide unexpected insights into the ecology and evolution of bumblebees and honeybees.

Uncovering new functions of a gene implicated in cancer growth opens new therapeutic possibilities.