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Hands of a person holding nasal spray, tablets, and tissues against a blurred beige background.
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Trial Tests Immune-Boosting Nasal Spray for Respiratory Virus Protection

A Phase 2 trial is testing a weekly intranasal spray that primes early immune defenses to reduce respiratory virus illness. The virus-agnostic approach targets multiple pathogens rather than a single virus.
Molecular structure model used in computational drug design.
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AI Model Guides Scientists Through the Synthesis of Complex Materials

Researchers developed an AI model that guides material synthesis by predicting multiple viable production pathways.
Sagittal view of anatomical brain model showing the brain stem, cerebellum, and cerebrum.
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New Target Emerges for Slowing Parkinson’s Disease Progression

Brain tissue analysis shows reactive microglia in Parkinson’s disease overexpress Fc gamma receptors, which may lead to inappropriate elimination of functional dopaminergic neurons. These findings suggest a treatment target for Parkinson's disease.
A tractor plowing a harvested field.
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Farm Waste Could Lock Away Carbon for Decades

A global analysis shows that fibrous crop residues could store carbon for decades when used in long-lived building materials.
Blood sample tubes in a lab rack. The tubes have barcodes and red or purple lids and are sitting in a yellow rack.
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Novel Blood Test Detects Early-Stage Cancers

By measuring randomness in DNA methylation, researchers identified early-stage cancers with high accuracy. The method outperformed traditional methylation tests.
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Some Bottled Water Is Worse Than Tap for Microplastics

Some brands of bottled water contain significantly higher levels of microplastics than tap water, suggests a new analysis that includes nanoplastics.
Illustration of a cell showing a range of contents in different colors, including nucleus, mitochondria and endoplasmic reticulum.
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Cells Adapt to Aging by Remodeling the Endoplasmic Reticulum

Researchers describe a new way by which cells adapt to the aging process: by actively remodeling the endoplasmic reticulum, one of the cell’s largest and most complex organelles.
Plastic anatomical model of a human brain.
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The Brain Microenvironment Shapes How Tumors Metastasize

A large multiomics study of brain metastases identified four molecular subtypes shaped by the brain microenvironment, not tumor origin.
A man sleeps on a bed with striped bed linen.
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Five Biological Sleep–Wake Patterns Identified

Researchers have identified five subtypes of the "early bird" and "night owl" sleep–wake patterns, each associated with different patterns of behavior and health.
A digital illustration of red cancer cells on a blue surface.
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Light-Based Nanotechnology Enables More Precise Cancer Treatment

Researchers developed light-responsive nanoparticles that selectively enter tumors and convert near-infrared light into heat.
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