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Inovio Biomedical Receives Additional Milestone Payment from Merck Relating to Electroporation Delivery System for DNA Vaccines
Inovio will receive $2 million resulting from the filing of a second IND application to the US FDA by Merck for a DNA- vaccine using Inovio's DNA delivery system.
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Fourth Genmab Antibody Developed Under Roche Collaboration to Enter Clinic
An IND has been filed with the FDA for the fourth Genmab antibody developed under the company's collaboration with Roche.
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ChemGenex Investigators Report Omacetaxine Effective in Killing CML Stem Cells in Animal Model Studies
Study demonstrates that omacetaxine had a direct anticancer effect on leukemic stem cells that was not exhibited by the tyrosine kinase inhibitor imatinib.
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Iloperidone Phase III Clinical Data Demonstrate Efficacy and Favorable Safety and Tolerability Profile
Titan Pharmaceuticals’ Phase III efficacy and safety trials demonstrate that iloperidone is associated with greater improvements in the symptoms of schizophrenia versus placebo.
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Cancer Cell Line Developed that is Resistant to new Cancer Therapy
Researchers found the HDAC inhibitor-resistant cell line resistant to many therapies but highly sensitive to heat shock protein 90 inhibitors, another emerging cancer treatment.
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Almac Sciences: “First in Man” Approach to Peptides
The approach offers development of peptide synthesis, full analytical support; GMP batches for Phase I and II, and finally support with CMC documentation.
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Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells Revealed
Researchers shows how two signaling pathways work together to assemble components of the protein complexes responsible for muscle-specific transcription.
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Sareum Announce Extension of Genentech Agreement
Sareum will continue to apply its skills in high throughput protein expression, purification and structure determination on drug discovery targets designated by Genentech.
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Rosetta Genomics Selects PCR as Platform for its microRNA-based Diagnostics to be Launched in 2008
Company’s first microRNA-based diagnostic tests will incorporate Nanogen's MGB probe technology.
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Researchers Test new Lab Method to Detect DNA Damage throughout the Genome
In laboratory experiments using budding yeast, the NCI scientists developed a new approach to determine the location of unrepaired breaks in DNA.
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