Model for Anticipating Viral Transmission Could Help To Optimize Disease Control MeasuresNews
Researchers propose a mathematical model to better understand the dynamics of the interactions between microorganisms within hosts and their transmission ability. The framework was applied on transmission data of the influenza virus, and offers to be a new tool for anticipating the consequences of microbial diversity and optimizing disease control measures.
Brain Connection Changes Linked to Post-Trauma DissociationNews
A team has found that brain imaging analyses can uncover changes in functional connections between brain regions linked to a specific individual’s dissociative symptoms following trauma.READ MORE
160 Genes Linked to Brain Shrinkage in 45,000-Person StudyNews
A new study implicates 160 genes in brain shrinkage seen on MRIs of 45,000 healthy adults. The shrinkage is in the cortex, the dimply outer layer of the brain that gives rise to thinking, awareness and action, and largely consists of gray matter.
In a study with potential impacts on a variety of neurological diseases, researchers have provided the first experimental evidence from a living organism to show that an abundant, star-shaped brain cell known as an astrocyte is essential for blood-brain barrier health.
A recent study published in the journal Nature Medicine describes a new Dual CAR T cell immunotherapy that can help fight HIV infection.READ MORE
Using information from the Swedish public health agency, researchers determined that BCG vaccination during infancy actually does not protect against the SARS-CoV-2 virus.READ MORE
New research has uncovered the presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).READ MORE
A new study compares the immune responses of adults and children with COVID-19. The study findings detected key differences that may contribute to understanding why children usually have milder disease than adults.READ MORE
A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.READ MORE
Researchers report novel findings concerning the therapeutic mechanisms of pomalidomide. They showed that pomalidomide causes the breakdown of a protein called ARID2. ARID2 promotes the "expression" of genes that are critical for the growth of multiple myeloma cells, so breaking down ARID2 is harmful to the cancer cells and beneficial to patients.READ MORE
A new study has laid out the steps that connect the neuromuscular disorder spinal muscular atrophy (SMA) to the mutations in the gene SMN1 that cause the condition. The research may explain how the mutations affect motor neurons and points the way to a better understanding of SMA.
In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefit.READ MORE