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Cryo-EM Reveals Ball-and-chain Action at Ion Channels

News   Mar 19, 2020 | Original story from Weill Cornell Medicine.

 
Cryo-EM Reveals Ball-and-chain Action at Ion Channels

Calcium-gated potassium channel MthK in closed, open and inactivated states, from left to right. Channel structure (blue), with one subunit removed for clarity; calcium ions (yellow); potassium ions (purple); membrane (grey); N-terminal inactivation peptide (red). The location of the peptide in the inactivated channel was identified in the structural analysis, whereas the location shown in closed and open channels is hypothetical. Credit: Dr. Crina Nimigean.

 
 
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