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Hundreds of Microproteins Identified in the Heart, Many Are Bound for the Mitochondria

News   May 31, 2019 | Original story from the Max Delbruck Center for Molecular Medicine

Hundreds of Microproteins Detected in the Human Heart

A whole series of tiny, previously unknown proteins are produced in the heart. A large portion of these microproteins migrate to the mitochondria, the cell’s energy powerhouses, after their production. The image provides proof that one of the new microproteins (red) reached the mitochondria (green). The yellow area on the third image shows that the mitochondrial signal overlaps with that of the microprotein inside the cells and that the microprotein is thus located in the mitochondria. The cell’s nucleus is blue. © Franziska Trnka, MDC



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Researchers at MIT have discovered an unexpected finding of consuming a ketogenic diet. Ketone bodies are known to activate signaling pathways implicated in stem cell differentiation. In a mouse model, they have shown that high levels of ketone bodies help the intestine to maintain a large pool of adult stem cells. These stem cells contribute to keeping the lining of the intestine healthy.


Storing Complex “Memories” in the DNA of Living Cells


Using a technique that can precisely edit DNA bases, MIT researchers have created a way to store complex "memories" in the DNA of living cells, including human cells.


Cell Suicide Could Hold Key for Brain Health and Food Security


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