Immunocore Named One of Fierce 15 Leading Biotechs of 2013
News Sep 26, 2013
Immunocore Limited has been named by FierceBiotech as one of 2013’s Fierce 15 biotechs, designating it as one of the most promising private biotechnology companies in the industry. This is Fierce Biotech’s eleventh annual Fierce 15 selection.
“Immunocore offers an interesting early-stage approach to rallying the immune system against cancer,” said FierceBiotech Executive Editor Ryan McBride. “Its T-cell receptor technology has taken many years to invent from scratch, and the hard work has begun to pay dividends with two recent pharma partnership deals.”
The company’s world-leading platform of bi-specific biological drugs, called ImmTACs (Immune mobilizing mTCR Against Cancer), exploit the power of T Cell Receptors (TCRs) to recognize intracellular changes that occur during cancer or viral infection.
This unique recognition ability of TCRs sets them apart from traditional antibody-based therapies that can only recognize changes on the surface of cells, and provides, for the first time, the ability to develop extremely potent targeted therapies for cancers that are poorly served.
A particular feature is that the ImmTACs can be directed to target and destroy only the cancerous cells, avoiding damage to healthy cells.
The most advanced ImmTAC drug, IMCgp100 for the treatment of melanoma, is in Phase I/II clinical trials in the UK and USA.
This summer, Immunocore announced two major partnership agreements with Genentech, a member of Roche Group, and GlaxoSmithKline to discover, develop and commercialize ImmTAC therapies against multiple targets.
James Noble, Chief Executive Officer of Immunocore, commented: “We are delighted to receive this prestigious award from FierceBiotech and be ranked among the top private biotech firms globally. This award recognizes 14 years of work to develop our technology and create a robust and reproducible platform, which has been validated through our two significant partnership deals, enabling our ImmTACs to be deployed as the basis of breakthrough treatments for cancers where there is a large unmet medical need.”
The Fierce 15 celebrates the spirit of being “fierce” - championing innovation and creativity, even in the face of intense competition.
An internationally recognized daily newsletter reaching more than 100,000 biotech and pharma industry professionals, FierceBiotech provides subscribers with an authoritative analysis of the day's top stories.
Every year FierceBiotech evaluates hundreds of private companies from around the world for its annual Fierce 15 list, which is based on a variety of factors such as the strength of its technology, partnerships, venture backers and a competitive market position.
A complete list of “Fierce 15” companies - the online newsletter’s eleventh annual selection - is available at www.fiercebiotech.com.
Single Blood Test 'CancerSEEK' Screens for Eight Cancer TypesNews
Johns Hopkins Kimmel Cancer Center researchers developed a single blood test that screens for eight common cancer types and helps identify the location of the cancer.READ MORE
Small Compound Able to Stave Tumor and Stop its GrowthNews
Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.READ MORE
Study Reveals How MRSA Infection Compromises Lymphatic FunctionNews
Infections of the skin or other soft tissues with the hard-to-treat MRSA bacteria appear to permanently compromise the lymphatic system, which is crucial to immune system function. Investigators describe how MRSA infection impairs the ability of lymphatic vessels to pump lymphatic fluid to lymph nodes in mouse models, which may contribute to the frequent recurrences of MRSA infection experienced by patients.