Nanogen Expands Patent Portfolio in Genetic Analysis Technologies
News Dec 23, 2005
Nanogen, Inc. has announced that its subsidiary Epoch Biosciences has been issued two patents by the U.S. Patent and Trademark Office for technologies related to genetic analysis.
The patents further bolster Nanogen's intellectual property position in genetic analysis technologies. U.S. Patent 6,972,339 "Compounds and Methods for Fluorescent Labeling," covers technologies that allow the high-throughput synthesis of fluorescently labeled nucleic acid probes and primers.
The second, U.S. Patent No. 6,972,328, "Non-aggregating Non-quenching Oligomers Comprising Nucleotide Analogs, Method of Synthesis and Use Thereof" relates to the synthesis and use of pyrazoloprimidine and 7-deazapurine nucleosides as replacements for the natural guanosine nucleoside in diagnostic nucleic acid oligomers.
"Our extensive investment in the development of genetic analysis technologies is paying off with the building of a strong IP portfolio in real-time PCR, mirroring our strong position in electronic microarrays," noted Howard C. Birndorf, chairman and chief executive officer of Nanogen.
"As molecular diagnostics gains further market penetration, these underlying technologies position Nanogen to address labs' needs with differentiated advanced diagnostic products."
The '339 patent describes fluorescent dyes and methods of preparation of fluorescently labeled biological probes including the high-throughput manufacturing of nucleic acid probes and primers that are used in Nanogen's MGB Alert™ and MGB Eclipse® assay formats.
The manufacturing methods covered by the '339 patent may be applicable to other genomic analysis formats used in competitors' DNA sequencing, genotyping and gene expression analysis assays.
The '328 patent relates to the use of pyrazolopyrimidine and 7-deazapurine nucleosides as replacements for the natural guanosine (G) nucleoside in nucleic acid probes.
Avacta Group plc announces successful outcome of “Gene Delivery” collaboration with FIT BiotechNews
Sustained production of Affimer drugs by muscle tissue in vivo could lead to major patient and commercial benefits.READ MORE
SCRaMbLE Speeds Up Yeast EvolutionNews
Scientists have created a new way of speeding up the genome evolution of baker’s yeast Saccharomyces cerevisiae. This is to develop a synthetic yeast strain that can be transformed on demand, making it industrial applications such as the mass production of advanced medicines to treat illnesses such as malaria and tuberculosis (TB).READ MORE
Artificial Cellular Compartments BuiltNews
How to install new capabilities in cells without interfering with their metabolic processes? A team from the Technical University of Munich (TUM) and the Helmholtz Zentrum München have altered mammalian cells in such a way that they formed artificial compartments in which sequestered reactions could take place, allowing the detection of cells deep in the tissue and also their manipulation with magnetic fields.READ MORE