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New Version of CRISPR Corrects RNA Defects Linked to Huntington’s, ALS

News   Aug 15, 2017 | Original story from University of California, San Diego

 
New Version of CRISPR Corrects RNA Defects Linked to Huntington’s, ALS

These are muscle cells from a patient with myotonic dystrophy type I, untreated (left) and treated with the RNA-targeting Cas9 system (right). The MBNL1 protein is in green, repetitive RNA in red and the cell’s nucleus in blue. MBNL1 is an important RNA-binding protein and its normal function is disrupted when it binds repetitive RNA. In the treated cells on the right, MBNL1 is released from the repetitive RNA. Credit: UCSD

 
 
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