We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Painkiller Caution To Avoid Kidney Damage

Painkiller Caution To Avoid Kidney Damage

Painkiller Caution To Avoid Kidney Damage

Painkiller Caution To Avoid Kidney Damage

Read time:

Want a FREE PDF version of This News Story?

Complete the form below and we will email you a PDF version of "Painkiller Caution To Avoid Kidney Damage"

First Name*
Last Name*
Email Address*
Company Type*
Job Function*
Would you like to receive further email communication from Technology Networks?

Technology Networks Ltd. needs the contact information you provide to us to contact you about our products and services. You may unsubscribe from these communications at any time. For information on how to unsubscribe, as well as our privacy practices and commitment to protecting your privacy, check out our Privacy Policy

Research has found that prescriptions of non-steroidal anti-inflammatory drugs (NSAIDs) reduced over the two years before the pandemic. However, they were still being given to some people at high risk of kidney damage.

The study was led by Dr Simon Fraser, Associate Professor of Public Health at the University of Southampton.

Avoiding kidney damage

NSAIDs are commonly prescribed to treat pain and inflammation. However, they can cause serious complications such as acute kidney injury (AKI).

This is where a person’s kidneys suddenly stop working properly. It can range from minor loss of kidney function to complete kidney failure.

Without quick treatment, abnormal levels of salts and chemicals can build up in the body. This affects the other organs’ ability to work properly.

If the kidneys shut down completely, the person may need dialysis or a kidney transplant. It can be fatal.

Prescriptions in those at higher risk

The researchers analysed data on 702,265 adults from a large primary care database in Hampshire to investigate NSAID prescriptions over two years.

Their results, published in BJGP Open, suggested a general decrease in NSAID prescriptions. This included in those at higher risk of developing AKI.

However, it revealed that some people at higher risk of developing AKI were still being prescribed NSAIDs. These included older patients and those with long-term conditions like chronic kidney disease and diabetes.

Dr Fraser said: “This study shows concerning signs that NSAIDs are still being prescribed to some people at high risk of kidney damage. Most prescribers are well aware of the risks of NSAIDs, particularly of inflammation and bleeding in the gastrointestinal tract, but our study reveals a need for greater attention to this AKI risk. GPs, nurse prescribers and pharmacists need to be aware and consider stopping (or not prescribing) NSAIDs in high-risk patients.”

Reference: Lin SX, Phillips T, Culliford D, et al. Characterising risk of non-steroidal anti-inflammatory drug-related acute kidney injury: a retrospective cohort study. BJGP Open. 2022. doi :10.3399/BJGPO.2021.0208

This article has been republished from the following materials. Note: material may have been edited for length and content. For further information, please contact the cited source.