Tecan Platforms Improve Microarray Throughput and Research Quality in South Africa
News Mar 10, 2008
Researchers at the Centre for Proteomics and Genomics Research (CPGR) in Cape Town, South Africa, have established a high throughput biological research platform with a number of automated microarray processing systems from Tecan, including an HS 4800™ Pro Hybridization Station with the new QuadChamber™, a HydroFlex™ system and an LS Reloaded™ laser scanner.
The CPGR uses a wide range of microarray-based techniques in a variety of collaborative projects to investigate diseases that are prevalent in South Africa, such as tuberculosis (TB), HIV/AIDS, malaria and cancers.
Dr. Reinhard Hiller, Managing Director of the CPGR, explained: “We set up the automated platform in order to increase our assay throughput and quality, while minimizing our costs and manual procedures. We are now fully equipped for processing almost all existing slide-based microarray formats, including genomic DNA, microRNA (miRNA) and protein microarrays.”
“We have had a fantastic experience with the Tecan HS 4800 Pro Hybridization Station, it is really versatile and it performs all steps of the hybridization process, improving the quality of our results. Tecan has even customized our HydroFlex to provide automated incubation and washing of 16-plex protein microarray slides, such as the cytokine profiling arrays from GenTel BioSciences.”
In treating inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.