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Urge To Merge: Understanding How Cells Fuse

News   May 28, 2020 | Original story from the University of Texas Southwestern Medical Center

 
Urge To Merge: Understanding How Cells Fuse

Multiple actin filaments (magenta) are organized around a dynamin helical polymer (rainbow colored) in this model derived from cryo-electron tomography. Recent UTSW research shows that by bundling F-actin, dynamin increases the mechanical strength of the actin cytoskeleton and enables the formation of invasive membrane protrusions during cell-cell fusion. This unique multifilament bundling mechanism may be generally applicable to other cytoskeletal remodeling events involving dynamin and actin. Credit: UTSW

 
 
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