Latest Posters
Poster
Molecular Dynamics Study of Binary Mixture Lubricating Film in Hard Disk Interface
As distance between the HMS in HDD shrink,there is a need for usage of binary mixture lubricants to overcome the problem of retention and replenishment of lubricants on HDD surface. In this work, lubrication performance of binary mixture will be modelled using MD simulation based on a coarse-grain spring model using Euler Algorithm.
Poster
Potential of the strain of entomopathogenic fungus Isaria fumosorosea CCM 8367 as a biological control agent against Cameraria ohridella and other pests
Strain CCM 8367 of Isaria fumosorosea (syn. Paecilomyces fumosoroseus) was isolated in the Czech Republic from lepidopteran pest and is deposited as a patent culture in the Czech Collection of Microorganisms in Brno. The aim of our study was to evaluate the effect of this strain on Cameraria ohridella, Leptinotarsa decemlineata and Spodoptera littoralis. Comparison with Apopka 97 strain isolated from commercial biopesticide PreFeRal WG (Biobest, Belgium) was made.
Poster
New Culture Medium Creates Immune Tolerance Between Two Allogeneic Tissue Cells
We discovered that in vitro high dose of Progesterone (P) together with FGFa, EGF, VEGF, LPS had dual effect on Liver tissue cells: increased multiplication of Hepatocytes and suppressed all non-parenchymal (NP) liver tissue cells and created immune tolerance between two allogeneic mice Liver tissue
Poster
The use of the IV microtracer technique to drive formulation optimisation
Strategy: Use IV microtracer techniquer to de risk compounds with PK issues and drive formulation development
Poster
Addressing the challenges of poor solubility: Rapid development and clinical evaluation of a lipid based formulation to enhance oral bioavailability of amuvatinib (MP-470)
Physiochemical and biopharmaceutical properties of new chemical entities are presenting increasing challenges to successful oral drug delivery. Here we present data on amuvatinib, a novel multi-targeted tyrosine kinase inhibitor specifically designed to be a potent inhibitor of mutant c-Kit and PDGFRalpha.
Poster
Quality Standards for 14C API for use in human clinical studies
The Good Manufacturing Practice (GMP) state that the active pharmaceutical ingredient (API) intended for use in early stage clinical trials should be of "suitable" quality. The Clinic Ready quality standard ensures that the API is synthesised with all the appropriate documentation to facilitate QP release of the final IMP for guman clinical dosing.
Poster
Elucidation of the Relative Bioavailability of a Drug Candidate from Different Regions of the Human Gastrointestinal Tract
This poster describes a pharmacokinetic study to investigate the relative absorption of an NCE from different regions of the human gastrointestinal tract, to support potential development of a sustained-release formulation.
Poster
Investigating Viral dynamics
Analysis of SIV next generation sequencing data for the estimation of escape rates in different animal groups and tissue compartments.
Poster
Role of PPARd in satellite cells and muscle differentiation
Investigating the result of PPARd mutation in the myogenic progenitor cells
Poster
Prognostic Factors for Refeeding Syndrome in Head and Neck Cancer Patients
Head and neck cancer sufferers are inherently at risk of refeeding syndrome, which had a prevalence of 9.5% in our series. Our results suggest that site of tumour (but not tumour or nodal staging) is a prognostic indicator for developing refeeding syndrome.
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