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A growing demand for study of cells within biologically realistic, in vitro, microenvironments requires a paradigm shift in cell culture technology: from cell culture on 2-D, rigid substrata to cell growth within a 3-D space, defined by malleable materials composed of biologically “smart” compounds.1, 2 Therapeutic issues addressed by tissue engineering and regenerative medicine require similar materials, customized for human application in a wide variety of treatment circumstances: ranging

The implementation of an RFID solution based on web services is demonstrated. The solution has three components.

Matrix elimination is a method of sample preparation that removes certain matrix species from a sample, typically by specifically binding matrix species to a solid phase. Interfering compounds can be removed before the analyte determination, thus improving the quality of results as well as lengthening the lifetime of consumables such as columns.

Spinocerebellar ataxia type 1(SCA1) is an inherited cerebellar neurodegenerative disorder caused by a polyglutamine tract expansion in the ataxin-1 protein.

Using a proprietary, low-melting, deactivated glass we have developed a novel instant Meltfit™ connection. Reliable connectors are made in-situ in less than a minute.

Asbestos related lung disease is likely to increase. Smoking, apart from being the major risk factor for lung cancer, may be a co-factor in the development of asbestos in lung disease. The Health and Safety Executive report mentions the high rate of smokers in asbestos related industry (1). We have reviewed our local population of asbestos workers to explore that further.

The heating of soil during fires may result in organic matter loss. The ratio of combustion enthalpy of soil organic matter to the alpha-beta quartz transition enthalpy can be used to compare heated and unheated soil. This eliminates the need to weigh samples and is insensitive to differences in water content between heated and unheated soils, making possible in-situ applications in field sites.

Half of rural Guatemala's population is indigenous; most births are attended at home by traditional midwives. Perinatal mortality is 2nd highest in Latin America. We administered a survey and implemented a training aimed at reducing perinatal mortality.

The University of Kansas in collaboration with PerkinElmer Inc. worked on looking at the comparison of the AlphaLISA Technology and an Electrochemiluminescence Technology to measure assay windows, lower and upper detection limits and intra - and inter-assay precision. In this study, three AlphaLISA no-wash assays, which employ a faster and less complex protocol, were found to deliver highly sensitive and accurate results, equivalent to those obtained in ECL technology.

In synthetic biological systems, cell lysis can be used to engineer programmed cell death and also to release proteins in extra-cellular environment, when secretion is not feasible. In this work, a promoterless lysis device called BBa_K112808, present in the Registry of Standard Biological Parts, was studied. A 3OC6-HSL inducible promoter was cloned upstream of the lysis device and used to characterize it.