Latest Posters
Poster
Automated Nanolitre Hit Automated Nanolitre Hit - Picking using a Mosquito® X1 Low Volume Pipettor
The mosquito® X1 offers precision sampling of any individual well in 48-, 96-, 384- or 1536-well plates. This enables researchers to quickly select small volumes of “hits” from primary screening plates and transfer them directly to the next screening stage without further dilution. mosquito® X1's disposable pipette tips guarantee zero cross-contamination.
Poster
High Throughput Screening of Biocompatible Polymers
The aim of this project was to develop high throughput screening methods using an IMSTAR Pathfinder™ High-content imaging platform to support the analyses of polymeric materials synthesised using a parallel approach. This was achieved by developing arrays of polymeric materials.
Poster
Cultures of Erythroid Precursors in the Screening of Gamma-Globin mRNA and Fetal Haemoglobin Inducers used for a new Approach in Thalassemia and Sickle Cell Anemia Therapy
Our group studied several inducers of erythroid differentiation. In the present study we demonstrate that rapamycin induces an increase of HbFproduction in erythroid precursors. This compound is able to increase gammaglobin gene expression in stem cells from blood of normal subjects as well asbeta-thalassemia patients.
Poster
A Solution for Low Volume Pipetting Applications Requiring High Accuracy of Sample Placement
Mosquito’s unique positive displacement disposable tips and precise X, Y and Z movements allow smaller drops with accurate and repeatable volumes to be positioned very precisely. This ability is essential for successful assay miniaturisation and the set-up of more effective serial dilutions or protein crystallography screens.
Poster
Facilitating Low Volume Protein Crystallography Set-ups Using the Mosquito® Liquid Handler
The mosquito® (TTP LabTech) offers fast positive displacement pipettingfor accurate and reproducible aspiration and dispensing throughout the 50 nL-1.2 µL range, producing CVs of <8% at 50 nLirrespective of viscosity. Mosquito’s micropipettes are also disposable, thus guaranteeing zero cross-contamination where required.
Poster
A Solution for Serial Dilution of Compounds in 1536-Well Microplates
High-density screening platforms are an integral part of any successful high-throughput screening facility. The reduced assay volumes associated with increasing well density lowers reagent costs, accelerates assay throughput, and can improve assay quality and reproducibility by minimizing assay duration.
Poster
Application of Microarrays in Process Analytical Technologies A First Step Towards Real Time Product Release
Application of microarrays during process development helps to gain insight in biological processes involved in product formation, increasing process understanding.
Poster
A 1H-NMR Based Metabonomics Study of Urine and Plasma Obtained from Healthy Human Subjects
An investigation on the plasma and urine samples of healthy male volunteers designed to evaluate the variability in metabonomic data, when severe life-style and dietary restrictions are imposed.
Poster
From Medicinal Plants to Bioactive Drugs
The aim of our study was to analyze the antiproliferative activity effects on human tumor cell lines and the differentiating activity on human erythroleukemic K562 cells of different extracts derived from medicinal plants of Bangladesh and Lebanon.
Poster
Novel Lewis Acid Catalyzed (E)/(Z)-Arylidene Thiohydantoin Formation
The novel Lewis acid catalyzed condensation of aldehydes with 3-alkyl-1-methyl-thioxo-imidazolidin-4-ones (thiohydantoins) to generate the corresponding (E)/(Z) 5-arylidene-3-alkyl-1-methyl-2-thioxo-imidazolidin-4-ones (arylidene thiohydantoins) is presented. A survey of various catalysts was conducted (either indium(III) triflate, aluminum trichloride, or boron trifluoride diethyl etherate) and compared with the uncatalyzed reactions.
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