We've updated our Privacy Policy to make it clearer how we use your personal data. We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement

Latest Posters

New Proteomic Subfractionation Surfaces – Innovative Technology for the Improved Resolution of Serum Proteins content piece image
Poster

New Proteomic Subfractionation Surfaces – Innovative Technology for the Improved Resolution of Serum Proteins

The data presented herein demonstrate the unique profiling capabilities of each ProFACT™ surface library subfraction and the collective resolution of 69 non-redundant proteins, calibrated and quantified from image analysis of SDS-PAGE profiles.
Rapid Solution Exchange and Ligand-Gated Channel Studies on the PatchXpress 7000A Automated Patch Clamp System content piece image
Poster

Rapid Solution Exchange and Ligand-Gated Channel Studies on the PatchXpress 7000A Automated Patch Clamp System

The PatchXpress® 7000A patch clamp system is an automated electrophysiology workstation that allows users to increase throughput of research quality recordings and to measure ion channel activity from nearly any channel type.
GeneGlobe — The World's Largest Database of Matching siRNA and RT-PCR Assays content piece image
Poster

GeneGlobe — The World's Largest Database of Matching siRNA and RT-PCR Assays

GeneGlobe is an easy-to-use, comprehensive Web portal that allows you to find information about, search for, and order high-quality products for human, mouse, and rat genes.
siRNA Design Including Secondary Structure Target Site Prediction content piece image
Poster

siRNA Design Including Secondary Structure Target Site Prediction

Preliminary data underlines the correlation between the siRNA knockdown efficiency and the local free energy of the mRNA target site. There is a strong evidence that considering the mRNA secondary structure within the siRNA design algorithm will lead to more efficient siRNAs.
KingFisher - A Multifunctional Tool for Proteomics content piece image
Poster

KingFisher - A Multifunctional Tool for Proteomics

In the proteomics area with the increasing capacity of the mass spectrometers, sample preparation is becoming a limiting step for protein identification. Magnetic particle based technology provides a rapid and easy solution for automation of the sample preparation step.
New 3D Black Substrate for Protein Microarrays with Improved Dynamic Range content piece image
Poster

New 3D Black Substrate for Protein Microarrays with Improved Dynamic Range

A competitive study analysing the background fluorescence and the detectable concentration range of a chosen antigen is presented. An Affymetrix Spotting roboter 417 arrayer was used for protein dotting. The analysis is based on fluorescence scanning experiments with an Affymetrix 428 array scanner at a gain of 60. Data analysis was made with ImaGene Premium 5.5.3 by Biodiscovery Inc.
High Throughput Technologies (HTT) content piece image
Poster

High Throughput Technologies (HTT)

This article aims to provide, with several real HTT system examples, a brief insight into how common, discrete tasks to HTT can be integrated into flexible, high throughput, automated systems as part of a corporate HTT strategy.
Optimizing the hERG Assay on the PatchXpress 7000A System for Compounds that Demonstrate Non-specific Binding content piece image
Poster

Optimizing the hERG Assay on the PatchXpress 7000A System for Compounds that Demonstrate Non-specific Binding

Eight compounds, astemizole, pimozide, dofetilide, cisapride, terfenadine, flunarizine, quinidine and imipramine were used to evaluate the effect of different assay conditions to overcome the effects of non-specific binding in our hERG assay on the PatchXpress 7000A system.
Reducing the Synthetic Burdens of Lead Structure Optimization: A Novel Software-Aided Approach content piece image
Poster

Reducing the Synthetic Burdens of Lead Structure Optimization: A Novel Software-Aided Approach

At the later stages of drug optimization it is beneficial to augment the select ADME properties of leads by making small structural changes that do not introduce any negative effects on the activity or toxicity profiles. By combining physicochemical property predictors and a critically evaluated database of biologically-acceptable substituents, the synthetic chemist can evaluate and reduce the number of derivative compounds that need to be synthesized to achieve optimal drug-like properties.
Development of an Analytical Data Management System (ADMS) to Accelerate the Selection of a Suitable API Form Through Salt and Polymorph Screening content piece image
Poster

Development of an Analytical Data Management System (ADMS) to Accelerate the Selection of a Suitable API Form Through Salt and Polymorph Screening

In this work, we discuss the acceleration of the preformulation process through the use of modern software systems. The data system discussed can read, process, store, retrieve, visualize and report a wide variety of data type—XRD, Raman, HPLC, NMR, TGA, DSC, chemical structures, properties and images—in a centralized and homogeneous way. A pilot study at a pharmaceutical company demonstrated possible time savings between 20% and 80% at various points in the preformulation workflow.
Advertisement