Latest Posters
Poster
Advanced Dryness Detection for Improved Throughput and Yield during Evaporation
In many laboratories across a wide range of disciplines, removal of solvent from dissolved sample is a routine, daily procedure. This article demonstrates the great importance of paying sufficient attention to closely monitoring the drying process and presents solutions to save time and prevent sample loss.
Poster
Combining Lyophilization and Centrifugal Evaporation
Creating a fast drying process that results in soft, unattached & rapidly re-suspendable dry sample.
Poster
Metabonomics, Dietary Influences and Cultural Differences: A 1H NMR-Based Study of Urine Samples Obtained From Healthy British and Swedish Subjects
Here, we describe two investigations on healthy subjects designed to evaluate the variability in metabonomic data, in view of dietary influences and cultural trends.
Poster
siRNA Design Including Secondary Structure Target Site Prediction
Preliminary data underlines the correlation between the siRNA knockdown efficiency and the local free energy of the mRNA target site. There is a strong evidence that considering the mRNA secondary structure within the siRNA design algorithm will lead to more efficient siRNAs.
Poster
Optimisation Workflow for the Production and Processing of High Quality Microarrays Applications in DNA, Peptide, antibody, and Carbohydrate Microarraying
We have developed a workflow for optimisation of array preparation and for processing protocols. Only 4 independent model experiments and solvent, immobilisation and blocking conditions. Optimal conditions or high quality microarray experiments were determined and used for array production and slide processing at the FGCZ.
Poster
Screening and Profiling for Kinases: Development of a Unique and Versatile Platform
To build a unique kinase platform providing reliable and quantitative data, we have designed a flexible system with well-defined yet different assay conditions for each kinase. This platform minimizes interferences, including those from test compounds, and displays a homogeneous and generic assay format.
Poster
Primary Screening of a 1564 Compound Focused Diversity set Against the Human Cardiac Sodium Channel Nav1.5 Using the IonWorks Quattro System
We conducted a feasibility study for using the IonWorks™ Quattro system in a primary screen of a focused library (1564 compounds) for modulators of the cardiac sodium channel Nav1.5 (hH1), an important target for anti-arrhythmia therapeutics.
Poster
High Throughput Automated High Content Screening using a BioCube™ System and Microplate Cytometry
Here, we model the integration of the Protedyne BioCube System and the Acumen Explorer for practical high-throughput, high content screening of protein kinases.
Poster
Diagnostic Genotyping of Drug Metabolising Enzyme Genes on Microarray: The DrugMEt™ Pharmacogenetic IVD Test
A microarray test for in vitro diagnostic use that contains 27 SNPs from 8 different genes with a proven role in the metabolism of major drugs and that may be processed using regular laboratory instrumentation and a range of different scanners.
Poster
Incorporation of Nanolitre Pipetting Technology into Medium and High Throughput SNP Genotyping Platforms at KBiosciences
This poster will describe the current process employed by KBiosciences. The vital role spot-on™ technology, incorporated into the Equator™ benchtop robotic liquid handling instrument, has played in improving performance and reducing costs are highlighted.
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