Latest Posters

This poster provides an overview of the data standards work initiated between several parties, our current work, and the plans towards showcasing an example of a set of proteomics data standards at work in a large scale clinical proteomics setting, in a biomarker discovery context.

Here we present the SIB concept, based on macrocyclic libraries in which the ring size is varied in gradual manner (conformational diversity). This allows selection of bioactive molecules based on their conformational complementary.

In this study, we have used microplate cytometry for the phenotypic profiling of both siRNA and miRNA libraries. Data are presented for cell proliferation and cell cycle analysis using propidium iodide nuclear staining and an Acumen Explorer™ laser-scanning fluorescence microplate cytometer.

In this work we compare two measurement parameters, the fluorescence intensity (FI) and fluorescence lifetime (FLT), which could be acquired efficiently in a multi parameter readout from one and the same measurement.

Results suggest that random priming is the optimal method for expression analysis of long genes. This method of RT may be appropriate for alternatively spliced genes and for genes without unique probes in the 3’-region.

The Universal Linkage System (ULS™) is a platinum-based technology that allows direct labeling of proteins and nucleic acids with a large variety of labels and haptens, including many fluorophores, biotin, and dinitrophenol.

DeCyder™ MS Differential Analysis Software (DeCyder MS) is a new tool for visualization, detection, identification and label-free relative quantification of LC-MS and LC-MS/MS data.

We present here an online system to handle Affymetrix sample submission and tracking, job management and lab processing. Many current microarray database solutions tend to focus on post sample-processing analysis. GenomeLIMS allows recording of all sample processing steps, there are no expression data analysis functions.

Using a novel quantitative real-time PCR assay, specific to the mature product, the expression level of a selected group of miRNAs was measured across a set of 30 primary adult acute myeloid leukemia (AML) with a normal karyotype.