Latest Posters

*Simplified detection and Component Extraction algorithm from LC-MS and GC-MS datasets
*New improved algorithm based on ion threads
*Reduced number of parameters to select for analysis
*Reduced false positives leading to reduced analysis time

Analysis of Extract Drying Criteria for Oil & Grease Method 1664A/B

The purpose of this research is to design a cell model in which ER stress caused by tau accumulation can be generated, and then investigated for changes in different ER stress-associated proteins.

Bacteria that live in the airways need something to eat: they mainly use host derived biochemicals, for example glucose. When levels of airway biochemicals are dysregulated, bacterial colonisation increases, enabling infection. We investigated how changes in airway glucose effect bacterial infection.

Here we present a new prediction algorithm that determines the likelihood of biotransformation reactions, and subsequent metabolite identification, within an automated processing routine.

Sample preparation is a key step in the analysis process
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Parameters for evaporation and their impact on analysis have been discussed
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Improvements in matching the sample to the evaporation device characteristics can help reduce variability and improve recovery
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Examples for choosing a system based on sample volume, types of analytes, sample load, and initial investment considerations

During early drug discovery, the study of metabolism plays an essential role in determining which drug candidates move forward into development and later stages. As an alternative to traditional Data Dependent Acquisition (DDA), the use of MSE/All Ions Fragmentation (AIF) has become common in metabolite identification workflows for the analysis of metabolic hot spots. Here we present a solution for analysis of MSE/AlF in metID studies.

A femoral nerve defect model was adapted for the evaluation of proregenerative effects of extracorporeal shockwave therapy (ESWT). Functional evaluation, histology and qRT-PCR data show differences between sensory and motor-derived nerve transplants and a pro-regenerative effect of ESWT. These data provide evidence for the clinical application of ESWT after autologous nerve transplantation as a novel non-invasive method.

A summary of the Disease Modeling Project for the MODEL-AD consortium.

Necrotizing fasciitis is a serious bacterial skin infection that spreads quickly and kills the body's soft tissue. The infection is commonly called "flesh-eating infection," The bacteria include group A Streptococcus, Klebsiella, Clostridium, Escherichia coli, Staphylococcus aureus and Aeromonas hydrophila. Bacteria infect flat layers of a membrane known as the fascia, which are connective bands of tissue that surround muscles, nerves, fat, and blood vessels.