Efficient Management of Extractable and Leachable Data in Process Development
Extractable and leachable (E&L) studies are an important part of successful drug product development. This poster highlights a support application built to help project teams address the challenge of effective data management across product development.
Efficient Genotyping and Powerful Data Analysis
The Agilent ZAG DNA Analyzer system is a high-throughput capillary electrophoresis instrument designed for qualitative analysis of DNA samples up to 20,000 bp in size. Download this poster to discover a system that streamlines the genotyping process and can separate up to 96 samples simultaneously.
Improved Expansion of Neural Stem Cells with Gibco™ Heat Stable Recombinant Human Basic Fibroblast Growth Factor
Basic fibroblast growth factor (bFGF) is used in neural stem cell (NSC) media to maintain multipotency. Native bFGF rapidly loses biological activity when exposed to culture conditions (37°C), Heat Stable (HS) bFGF maintains > 90% homology to the native protein and ≥ 80% biological activity, even after 72 hours of exposure to 37°C.
Avoid Transcription Errors and Paper-Based Inefficiencies With STARLIMS Lab Execution System (LES)
Laboratory processes are often documented on paper, whilst the pressures laboratories face to remain compliant as well as demonstrate their capacity to deliver reliable results continues to escalate. Discover how STARLIMS LES can help you.
Accelerating Antibody Drug Development With Affinity Purification
The changing landscape for antibody-derived therapeutics, such as bi-specific monoclonal antibodies, Fab fragments and Fc-fusion proteins brings new purification challenges in the downstream processing of these molecules. Standard chromatography resins, such as Protein A, may not result in the most efficient purification process.
Assessing Chemical-Mediated in Thyroid Function In Vitro
Access this poster to discover in vitro approaches including recombinant deiodinase inhibition, thyroid peroxidase inhibition and rat sodium iodide symporter inhibition among others.
Isothermal Titration Microcalorimetry: An Essential Tool for Fragment-Based Drug Discovery
Download this poster to discover how ITC requires minimal assay development and sample preparation, allows early determination and elimination of false positives and can be used to identify fragments that will form a high-resolution co-crystal with the target protein.
One-Pot Borylation/Suzuki Couplings for Streamlined Synthesis of Compounds in Drug Discovery
Download this poster to discover how one-pot borylation/ Suzuki couplings to form sp2–sp2 C-C bonds achieves streamlined synthesis, in situ esterification using low-cost reagents and excellent functional group tolerance.
Assessing the Quality and Quantity of Cell-Free DNA
For circulating cell free DNA (ccfDNA) to be used in cancer research successfully, workflow standardization is essential. Access this poster to discover tips on optimal workflow control, how to yield smaller ccfDNA fragments and the differences in quantification and qualification of ccfDNA.
Interrogation and Modulation of the Immunosuppressive Activity of Human TAM-Like Macrophages Using In Vitro Cultures
Tumor associated macrophages (TAMs) can facilitate the proliferation of tumor cells and are able to suppress anti-tumor immune responses within the tumor microenvironment, making them a highly attractive target for the development of innovative cancer immunotherapies.