Latest Posters
Poster
Acoustic Startle Response as a Prognostic Tool for Traumatic Brain Injury
The Acoustic Startle Reflex (ASR) is a brain-stem mediated, tri-synaptic response to acoustic stimuli involving involuntary contraction of major muscle groups. Previous studies have demonstrated that this response is suppressed following the fluid-percussion model of traumatic brain injury (TBI). The possibility exists that the suppression of this response could be exploited for prognostic purposes.
Poster
Examining the Role of Arginase1 Overexpression in an Animal Model of Tauopathy
Because of the possible beneficial role of polyamines, metabolism of arginine by arginase is of interest. Recently, our lab has recently shown that arginase1 overexpression has the ability to reduce phosphorylated tau and neurofibrillary tangles in rTg4510 and PS19 tau transgenic mice. Based on these data, we utilized the transgenic tetO MAPT*P301L mouse model to examine a potential therapeutic gene of interest, arginase1, in an animal model of tauopathy.
Poster
Neuroprotection by T-Lymphocytes and Stem Cells After Ischemic Stroke
In this study, regulatory T-cells and BMSCs were shown to be neuroprotective following ischemic treatment of primary rat neurons.
Poster
Stress-induced nucleocytoplasmic shuttling of TDP-43 is controlled by eIF-5A hypusination
In this experiment, we sought to determine the function of hypusinated eIF5a in relation to TDP-43 pathology in nuclear and cytoplasmic compartments under cellular stress.
Poster
Role of TDP-43 in activation of the brain inflammatory response
Profiling of inflammatory cytokines, receptor and kinases in WT and TDP-43 overexpressing mice.
Poster
A luminescent solar concentrator-based photomicroreactor for energy efficient continuous-flow photocatalysis
The Luminescent Solar ConcentratorPhotomicroreactor (LSC-PM) is an innovative device for solar-powered continuous-flow photochemistry. It is constituted by an LSC lightguide that harvests solar photons and delivers them downshifted to the embedded microflow reactor.
Poster
Disruption of Normal Circadian Function in a Mouse Model of Tauopathy
This study is focused on elucidating how tauopathy disrupts normal circadian clock function at both the behavioral and molecular levels.
Poster
Measuring dynamic and real-time cAMP levels using cADDis2, a live-cell indicator for Gs and Gi signaling
Here, we introduce a new fluorescent cAMP indicator, cADDis2, capable of detecting dynamic changes in cAMP concentration in living cells.
Poster
Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2
We mimicked chronic exposure in smokers’ airways by continuously exposing BEAS-2B cells to TPM from 3R4F cigarette smoke or aerosol of the Tobacco Heating System 2.2 (THS2.2), a cMRTP, for 12 weeks.
Poster
Genomic Analysis of L5178Y tk+/- Cells and their Induced tk-/- Mutant Colonies
The goal of this pilot study was to exploit NGS technology with a view to shedding new light on the genome of cells used in the MLA, as well as the changes induced as a result of the exposure to mutagens.
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