Latest Posters
Poster
Detecting resistance associated variants in HCV and HIV
Objectives: to develop improved detection of clinically relevant viral mutations using ion torrent based NGS in an automated workflow.
Poster
Can a Unified Laboratory Intelligence Approach be Applied to E&L Studies?
Informatics technologies and software automation of workflows are becoming key strategic considerations for identification, elucidation, and characterization of extractables and leachables.
Poster
Automated Structure Verification: What are the Right Experiments and Processing?
The inclusion of expanded data types supports more accurate structure verification, decreasing the likelihood that false structures may pass through a verification process.
Poster
Inecalcitol Stimulates CD38 Expression in Multiple Myeloma and Acute Myeloid Leukemia Cell Lines
Inecalcitol is a vitamin D receptor agonist currently in Phase II clinical trial in AML (acute myeloid leukemia). Inecalcitol increases the expression of CD38 at the surface of 5 multiple myeloma cell lines; therefore, inecalcitol could potentiate the clinical response of MM patients to a therapeutic anti-CD38 antibody
Inecalcitol induces the expression of the CD38 antigen at the surface of 4 AML cell lines; thus, inecalcitol could render AML patients sensitive to a therapeutic anti-CD38.
Inecalcitol induces the expression of the CD38 antigen at the surface of 4 AML cell lines; thus, inecalcitol could render AML patients sensitive to a therapeutic anti-CD38.
Poster
Strategies for Improving RNAi Screening Success: Using a Ubiquitin-EGFP Assay to Identify Druggable Genes Required for Proteasome Function
This poster describes the approaches used to ensure effective delivery of siRNA molecules and to identify robust siRNA controls. It also provides the strategies used to validate compatibility of the RNAi automation platform with the phenotype being analyzed.
Poster
Integration of Data and Optimization of Workflows in Laboratory Automation
The iLAB Software Framework, a middleware connecting lab devices and higher level enterprise software systems, provides a plug-in architecture that can be adapted to individual lab environments.
Poster
Optimized Workflow for Single Cell Copy Number Profiling Using High Resolution Oligo CGH Arrays
Here we describe GenetiSure Pre-Screen, a same day, cost-effective, analysis workflow that combines whole genome amplification (WGA) with copy number (CN) profiling using high-resolution oligo CGH microarrays.
Poster
Functional Analysis of RAD51B and RAD23B SNPs using Circular Chromosome Conformation Capture (4C) in Human Prostate Cell Lines
The aim of this study is to understand the mechanism behind the association between single nucleotide polymorphisms (SNPs), lying in non-coding regions near or within RAD51B and RAD23B, and prostate cancer risk by analysing their interactions with the whole genome using Circular Chromosome Conformation Capture (4C).
Poster
Optimization of a Vacuum Ultraviolet Photoionization source for GC used with a High Resolution TOFMS
-Tune solution allows optimization of ion source parameters for
both proton transfer and direct ionization
-Independent ionization processes exist for M+ and MH+
-Optimizing for dopant signal intensity yields inferior results
-Degree of fragmentation remains relatively constant over a
range of source conditions
both proton transfer and direct ionization
-Independent ionization processes exist for M+ and MH+
-Optimizing for dopant signal intensity yields inferior results
-Degree of fragmentation remains relatively constant over a
range of source conditions
Poster
Preparation of Photonic Biosensors by Inkjet Printing Technology
In order to enable local functionalization of label-free optical waveguide biosensors in a cost effective mass-fabrication compatible manner, we investigate surface modification employing inkjet printing of functional polymers and UV-curable benzophenone dextran.
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