Latest Posters
Poster
Targeting Cancer Stem Cell-Related miRNAs for Prostate Cancer Therapy
The poster focuses on the pivotal function of miRNAs in tumorigenesis by regulation of self renewal and apoptosis via cancer stem cell signalling pathways with special focus on their regulation of Epithelial to Mesenchymal transition in metastatic prostate cancer.
Poster
A Reduced Workflow Solution for the Analysis of Gamma-Hydroxybutyrate (GHB) in Human Hair Samples Via an Automated Bead Mill as a Precursor to GCxGC-TOFMS and GC-HRT
- The Biotage Bead Ruptor 24 was effective in pre-treating hair samples prior to the extraction procedure.
- The enhanced chromatographic resolution of GCxGC-TOFMS and high resolving power of GC-HRT minimized interferences and facilitated accurate analysis of GHB in hair.
- The enhanced chromatographic resolution of GCxGC-TOFMS and high resolving power of GC-HRT minimized interferences and facilitated accurate analysis of GHB in hair.
Poster
An Alternative to Direct Probe: Pyroprobe Coupled to High Resolution Time-of-Flight Mass Spectrometry
Direct Pyroprobe is not a substitute for direct probe, but there is some overlap, as well as additional functionality. Direct probes coupled to LECO Pegasus instruments provide unique features:
– Time-of-flight mass spectra which shows little-to-no spectral skewing
– Automatic peak finding and spectral deconvolution for better identification
– Pegasus HT has a very low maintenance source which is beneficial for direct analysis techniques
– Time-of-flight mass spectra which shows little-to-no spectral skewing
– Automatic peak finding and spectral deconvolution for better identification
– Pegasus HT has a very low maintenance source which is beneficial for direct analysis techniques
Poster
A FastGC Proton-Transfer-Reaction Quadrupole Ion Guide Time-of-Flight (PTR-QiTOF) Mass Spectrometer
In order to identify and quantify isomeric compounds independently in real-time, we introduce a novel approach where we integrate a fast GC column (“fastGC”) into a PTR-QiTOF instrument. The outstanding sensitivity of the new PTR-QiTOF (up to 4,700 cps/ppbv) is crucial for applications where time per analysis is limited, e.g. nosespace in food and flavor research. Particularly, in these fields the chemical environment is normally very complex so that a high selectivity is essential as well.
Poster
Capillary Electrophoresis Coupled with Micro Free Flow Electrophoresis for High Speed Two Dimensional Separations of Biological Samples
We propose using micro free flow electrophoresis (µFFE) as a solution to the under sampling problem.
Poster
Integrating Fluorescent Carbon Nanodot Synthesis and Optical Detection of Methylmercury
In the last years, a great interest toward development of optical nanoprobes has arisen, so fluorescent nanomaterials have been implemented in analytical systems for the detection of several species. In this work, a novel assay that integrates the synthesis of fluorescent carbon dots (CDs) and sensing within one step, for the fast, sensitive and selective detection of methylmercury is presented.
Poster
Safety Of The 300 IR and 500 IR Doses Of A House Dust Mite Allergen Extracts Sublingual Tablet In Adults with Allergic Rhinitis
In a randomized, DBPC study in patients with HDM-associated allergic rhinitis, treatment with HDM sublingual tablets at doses of 300IR and 500IR was associated with a favorable safety profile. There was no appreciable difference in tolerability between the tested doses.
Poster
Safety Of A Sublingual Tablet of House Dust Mite Allergen Extracts In An Environmental Exposure Chamber Study
In an environmental exposure chamber (EEC) study, treatment with HDM sublingual tablets in patients with HDM-associated allergic rhinitis was generally well tolerated regardless of dose. While asthma and related symptoms were more common during the peri-EEC challenge periods, rates did not differ between active and placebo treatment.
Poster
Impact of Molecular Surface Charge on Electrical Impedance Spectroscopy Biosensing
Molecular surface charge was found to be the dominant parameter when monitoring protein binding events by Electrical Impedance Spectroscopy with a charged redox couple. A biosensing device was fabricated, and a physical model was derived to explain the results.
Poster
Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery
To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).
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