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Latest Posters

Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery content piece image
Poster

Droplet-on-Demand Platform for Biochemical Screening & Drug Discovery

To demonstrate droplet on demand applications towards study of biological entities encapsulated in nanoliter droplets. Interfacing a droplet on demand platform with microfluidic chips allows for merging and dilution of droplets. This feature is applied to encapsulate yeast cells (S. cerevisiae) and multicellular organisms (C. elegans).
Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry content piece image
Poster

Cell-Mediated Cytotoxicity Assay by High-Throughput Direct Cell Counting in Microplates using Fluorescence-Based Image Cytometry

In this work, we demonstrate a novel high throughput cytotoxicity detection assay using the Celigo Imaging Cytometry method. Utilizing imaging cytometry, direct cell counting of live fluorescent target cells can be performed, which is a direct method for assessment of cytotoxicity.
Analysis of Polymers, Additives and Contaminates in Medical Devices using Pyrolysis-GCMS content piece image
Poster

Analysis of Polymers, Additives and Contaminates in Medical Devices using Pyrolysis-GCMS

Pyrolysis GC-MS is a standard technique used to analyze industrial polymers. This poster will show the use of multiple temperature ramps to analyze for additives and contaminants, in addition to polymer identification, in several medical devices.
Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications content piece image
Poster

Long-term on-chip storage and release of liquid reagents for diagnostic lab-on-a-chip applications

We present a concept which enables on-chip storage of liquid reagents at room temperature and allows an easy implementation into pressure driven LoC devices.
Investigating the Effects of Commercial Antimicrobial Agents on Human Corneal Epithelial Cell Membranes content piece image
Poster

Investigating the Effects of Commercial Antimicrobial Agents on Human Corneal Epithelial Cell Membranes

Several commercial multi-purpose solutions (MPS) products contain polyhexamethylene biguanide (PHMB) and/or polyquaternium-1 (PQ-1) as antimicrobial agents. In this poster we report the effects of PHMB and PQ-1 on small unilamellar vesicles (SUV) that we have designed to mimic the average human corneal epithelial cell membrane.
Direct Targets Identification of a Bioactive Compound content piece image
Poster

Direct Targets Identification of a Bioactive Compound

Identifying protein partners of a small bioactive molecule is of great
interest in many aspects of life sciences and specifically in the drug
discovery and development process cycle. It is a support to (i) decipher
the mechanism of action after for example a “High Content” screening,
(ii) study “off-target” effects, (iii) adjust therapeutic indications and
clinical regimens of a drug and (iv) consider drug repositioning.
Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water content piece image
Poster

Aptamer-Based Electrochemical Biosensing Platform for Detection of Hormonal Pollutants in Water

A novel detection mechanism based on aptamers has been developed to detect small molecules as hormones, antibiotics, toxins, drugs, etc. For first time, an aptasensor to detect progesterone has been developed.
A Multiplexed Amplicon Sequencing Technology for FFPE and Circulating, Cell-free DNA content piece image
Poster

A Multiplexed Amplicon Sequencing Technology for FFPE and Circulating, Cell-free DNA

A novel amplicon approach allowing for hundreds of amplicons to be multiplexed in a single tube with a two workflow from sample to sequencer.
3D-Tissue/ Whole-blood Co-culture Models Combined  with Multi-Analyte Profile (MAP) Analyses for  In-vivo-like Immunopharmacology content piece image
Poster

3D-Tissue/ Whole-blood Co-culture Models Combined with Multi-Analyte Profile (MAP) Analyses for In-vivo-like Immunopharmacology

Human Organotypic Test (HOT) Systems aim at in-vivo like substance characterisation of all preparations meant to act on the human immune system.
Field Performance of a New Technology with the Potential to Identify Allergy and Asthma Triggers content piece image
Poster

Field Performance of a New Technology with the Potential to Identify Allergy and Asthma Triggers

This work introduces a very simple plug-and-play device that can sample air at a high volume flow rate with no moving parts. Aerosol particles are captured on electrodes and eluted for testing. We show that performance of the device is substantially equivalent to capture by pumping through a filter for immunological and molecular analysis.
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