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Why Use Supported Liquid Extraction To Develop a GLP Protocol for the H295R Steroidogenesis Assay? content piece image
Poster

Why Use Supported Liquid Extraction To Develop a GLP Protocol for the H295R Steroidogenesis Assay?

Environmental chemicals have the potential to perturb hormone systems, a finding that has led to recommendations for the testing of potential endocrine disrupting chemicals.
Restoring T Cell Function in Exhausted T Cells content piece image
Poster

Restoring T Cell Function in Exhausted T Cells

T cells can develop an exhausted phenotype due to prolonged antigen stimulation, resulting in reduced proliferative potential and loss of cytotoxic funtion. This can occur within the tumor microenvironment, allowing cancer cells to escape immune surveillance.
<i>In Vitro</i> Approaches To Risk Assess Chemical-Mediated Changes in Thyroid Function content piece image
Poster

In Vitro Approaches To Risk Assess Chemical-Mediated Changes in Thyroid Function

The hypothalamic-pituitary-thyroid axis (HPT axis) is conserved across vertebrate evolution. Perturbation of thyroid hormone homeostasis (THH) can lead to adverse effects in thyroid function affecting growth, metabolism and cognitive function.
Expanding Practical Education With Brightfield Imaging-Enabled Flow Cytometry content piece image
Poster

Expanding Practical Education With Brightfield Imaging-Enabled Flow Cytometry

Insights and Expanding Practical Education in a Core Facility With Brightfield Imaging-Enabled Flow Cytometry
Maximize mRNA Yield Using <i>In Vitro</i> Transcription  content piece image
Poster

Maximize mRNA Yield Using In Vitro Transcription

The growing use of RNA-based vaccines and therapies has focused much attention and effort on developing conditions for maximizing the yield and efficiency of the in vitro transcription (IVT) reactions used to produce mRNA. IVT procedures involve the biosynthesis of RNA from a linear DNA template containing an appropriate transcription promoter. But how do different buffer conditions and nucleotide concentrations impact the IVT reaction?
Lead Identification Screening Services in 3D content piece image
Poster

Lead Identification Screening Services in 3D

2D cultures often fall short in drug screening when it comes to clinical predictivity, but 3D models and high content services allow accurate and clinically relevant screens.
Optimized Expression of Membrane Proteins: New Tools for Difficult-To-Express Proteins content piece image
Poster

Optimized Expression of Membrane Proteins: New Tools for Difficult-To-Express Proteins

Membrane proteins are a notoriously difficult class of proteins to express, purify and characterize. Expression levels of membrane proteins in mammalian expression systems, the preferred system to generate native-like post-translational modifications, are often so low that yields are unsuitable for the intended downstream uses.
Fluorophore and Reagent Selection Guide for Flow Cytometry content piece image
Poster

Fluorophore and Reagent Selection Guide for Flow Cytometry

Researchers are always developing innovative applications for novel research areas, improving data quality and expanding the boundaries of experimental limitations.
Tackle Real-Time PCR Research Challenges content piece image
Poster

Tackle Real-Time PCR Research Challenges

Nucleic acid amplification and detection techniques are highly valuable tools that can be used across a wide range of applications... Real-time PCR, also known as quantitative PCR (qPCR), is the gold-standard for sensitive, specific detection and quantification of nucleic acid targets.
Selecting the Right HPLC Column content piece image
Poster

Selecting the Right HPLC Column

C18 columns have a broad applicability, from pharmaceuticals to food and environmental analyses. However versatile C18 columns are, they aren't the optimal stationary phase for every application.
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