A new High Content Screening Paradigm: Combination of Image Analysis Software and Microplate Cytometry
Poster Feb 01, 2007
Sarah Payne, Paul Wylie, Simon Carter and Wayne Bowen
Researchers are under increasing pressure to perform high content cell-based assays at throughputs compatible with primary screening. Where throughput is not an issue, microscope-based CCD imagers have predominated within the high content field, due to the breadth of biological assays that can be addressed by image analysis techniques. However, they have limited utility for screening due to their low throughput, limited field of view and generation of terabytes of image data.