A Novel Array- Based Assay for the Detection of Ig G-Mediated Food Intolerance
Poster Feb 01, 2007
Andrew Macdonald, Michael J. Walker, Michael S. Walker and Julie G. Reeve
We have developed a microarray based immunoassay to permit both greater food panel diversity and higher throughput testing.The Genarrayt™ 200+ Foods IgG test comprises of glass slides onto which 16 microarrays of over 200 different foods have been printed. Each microarray includes standards for quantitation and positive and negative controls for quality control. Food IgGs are detected by a novel fluorescent dye labelled anti-human IgG conjugate and results are measured using a laser scanner.
The immune system is a striking example of an integrated information system, engaged in coordinated host-protective activities. Organs-on-chip approach (OOC) models allow the direct simultaneous observation of hundreds of different cells, moving, interacting and responding to signals coming from the microenvironment nearby, that give access to a number of parameters describing the system that must be properly measured and elaborated.READ MORE