A Novel Ultrasonic Method for Characterizing Suspensions of Nanoparticles
Poster Jan 19, 2007
The UltraSonic Pulsed Doppler (USPD) technique is a novel ultrasonic-backscatter technique for characterizing nanoparticles. Using a single transducer and able to operate in almost arbitrary vessels on samples over a range of concentrations and opacities, the system can measure concentration, size (with precision exceeding that of DLS) and mechanical compliance (for particle functionalization monitoring). To date, the system has ‘imaged’ dendrimers, colloids, carbon nanotubes, polymer beads and protein.
Sample preparation is a key step in the analysis process
Parameters for evaporation and their impact on analysis have been discussed
Improvements in matching the sample to the evaporation device characteristics can help reduce variability and improve recovery
Examples for choosing a system based on sample volume, types of analytes, sample load, and initial investment considerations
Automated sample preparation reduces the costs per sample and minimizes sample handling errors. Usually expensive and highly specialized pipetting robots are used. However, most of these systems are not designed with a direct interface for LC-MS applications. In addition common pipetting systems are not optimized for smaller scale sample series. Here we present a new tool for liquid handling of whole blood samples and direct sample injection.READ MORE