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A Sandwich-Injection Method for Microchip Electrophoresis

A Sandwich-Injection Method for Microchip Electrophoresis content piece image
Abstract
We present a sandwich-injection method for controlling discrete sample injection in µ-CE. This method involves four accessory arm channels in which symmetrical potentials are loaded to form a unique parallel electric field distribution to confine the spreading of sample plugs and prevent sample leakage. The virtues of the novel injection technique were demonstrated with numerical models and experiments.