A Systematic Review of Lifestyle Modification in Adults with Non-Alcoholic Fatty Liver Disease
Poster Apr 04, 2012
C. Thoma, C. P. Day and M. I. Trenell, Newcastle University
Non-alcoholic fatty liver disease is an independent risk factor for type 2 diabetes and cardiovascular disease that affects about 30% of the adult population. There is no approved pharmacotherapy, thus lifestyle modification is broadly advocated as a treatment. Prior to this review, there was no systematic assessment of the evidence base for making lifestyle change recommendation in this group of patients.
Is Oxford Nanopore Technology Ready for Clinical Diagnostics?Poster
Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.READ MORE
CiPA Phase 2 Study: validation of an automated microelectrode array (MEA) assay of hiPSC-derived cardiomyocyte electrophysiology for cardiac safety evaluationPoster
These results support the use of hSC-CM and MEA technology for preclinical assessment of proarrhythmic risk within the proposed CiPA paradigm, and, more generally, demonstrate that automation of the CM-MEA assay can achieve high reliability and throughput for cardiac risk assessment in vitro.READ MORE