We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience. You can read our Cookie Policy here.

Advertisement
A Total Solution to Provide High Content Primary and Secondary Screening of a Compound Library
Poster

A Total Solution to Provide High Content Primary and Secondary Screening of a Compound Library

A Total Solution to Provide High Content Primary and Secondary Screening of a Compound Library
Poster

A Total Solution to Provide High Content Primary and Secondary Screening of a Compound Library

Abstract
G-protein coupled receptors (GPCRs) represent the largest and most frequently screened class of receptors. TTP LabTech recently published a novel approach using the Acumen Explorer with Invitrogen’s GeneBLAzer technology to measure GPCR activation in cell-based assays. This is multiplexed with a cytotoxicity readout to reduce false positives commonly identified in bulk fluorescence assays. TTP LabTech and Velocity11 have designed a fully automated, single platform using this assay to perform both primary and hit-confirmation screens on a 400,000 compound library in only one week.
Advertisement