A Valve-Controlled Microfluidic Sysytem for Rapid Two-Dimensional Electrophoresis
Poster Mar 10, 2006
Yiqi Luo, Bo Huang, Michael P. Bokoch, Richard N. Zare.
Overview(1) Rapid (350 s) two-dimensional electrophoretic separation of proteins in a PDMS microfluidic chip
(2) Valves located at the intersection allow the simultaneous sample transfer between the 1-D single channel and 2-D channel array
(3) Scanning confocal method extends the size of both 1-D channel and 2-D array thus providing higher peak capacity for practical application
(4) Combining with the silicon electrospray tip facilitates the connection of electrophoresis and mass spectrometry.
The immune system is a striking example of an integrated information system, engaged in coordinated host-protective activities. Organs-on-chip approach (OOC) models allow the direct simultaneous observation of hundreds of different cells, moving, interacting and responding to signals coming from the microenvironment nearby, that give access to a number of parameters describing the system that must be properly measured and elaborated.READ MORE